5-Bromo-2-iodopyrimidine CAS: 183438-24-6
Chemical Intermediates 2025-03-02
CAS: 183438-24-6
Purity: ≥99%
Capacity: 200mt/year MOQ: 218g
Application: Organic Intermediate
Standard: Enterprise export
Manufacturer: Jinan Finer Chemical Co., Ltd
Molecular Formula: C4H2BrIN2
Molecular Weight: 284.88
CAS Registry Number: 183438-24-6
Melting point: 99-103 ºC
5-Bromo-2-iodopyrimidine, with the CAS registry number 183438-24-6, is a versatile chemical compound primarily utilized as an intermediate in the synthesis of various pharmaceuticals and pesticides. This aromatic heterocyclic compound features a bromine atom and an iodine atom substituted on the pyrimidine ring, contributing to its unique reactivity and properties. Due to its distinctive structure, 5-bromo-2-iodopyrimidine serves as a key precursor in the preparation of pyrazinylpyridines, which are effective inhibitors of vascular endothelial growth factor receptor 2 (VEGFR2). Additionally, it is also employed in the synthesis of novel conformationally constrained glucagon receptor antagonists.
| Property Category | Details |
|---|---|
| Chemical Name | 5-Bromo-2-iodopyrimidine |
| CAS Number | 183438-24-6 |
| Physical Properties | |
| Appearance | Reagent grade: pale yellow solid or white to brownish crystalline powder |
| Melting Point | 99-103°C |
| Boiling Point | 341.0±34.0°C (predicted) |
| Density | 2.495±0.06 g/cm³ (predicted) |
| Chemical Properties | |
| Molecular Formula | C4H2BrIN2 |
| Molecular Weight | 284.88 g/mol |
| Solubility | Information not specifically provided, but generally soluble in organic solvents |
| Acidity (pKa) | -2.56±0.22 (predicted) |
| Light Sensitivity | Light sensitive, should be stored in a dark place |
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