4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-
Pharmaceutical Materials 2025-03-02
CAS NO: 162012-67-1
Molecular Formula: C14H7ClF2N4O2
Molecular Weight: 336.68
Appearance: It is a chemical intermediate used in the pharmaceutical industry.
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| Property | Description |
|---|---|
| Name | 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- |
| CAS Number | 162012-67-1 |
| Molecular Formula | C14H7ClF2N4O2 |
| Molecular Weight | 336.68 g/mol |
| Synonyms | – N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine |
| – Intermediate for Canertinib synthesis | |
| – 4-[(3-Chloro-4-fluorophenyl)amino]-7-fluoro-6-nitroquinazoline | |
| Category | Chemical Intermediate |
| Physical State | Typically solid |
| Appearance | Off-white to pale yellow crystalline powder |
| Solubility | Soluble in organic solvents such as DMSO, DMF; slightly soluble in water |
| Storage Conditions | Store at room temperature, in a sealed container, away from moisture and light |
| Applications | Used as a key intermediate in the synthesis of pharmaceutical compounds, |
| particularly in the development of kinase inhibitors and anticancer agents. | |
| Safety Considerations | Handle with care; use appropriate personal protective equipment (PPE) |
| due to potential hazards associated with chemical handling. |
