4-Piperidinemethanol

Pharmaceutical Materials 2025-03-02

CAS Number: 3433-37-2

Molecular Formula: C6H13NO

Molecular Weight: 115.17

Appearance: Clear liquid

Usage: It is widely used as a chemical intermediate in the synthesis of pharmaceuticals and other organic compounds.

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Attribute Details
Chemical Name 4-Piperidinemethanol
CAS Number 6457-49-4
Synonyms 4-(Hydroxymethyl)piperidine, Piperidine-4-methanol, 4-Methanolpiperidine
Molecular Formula C6H13NO
Molecular Weight 115.17 g/mol
Appearance White to off-white powder or crystalline solid
Melting Point 55-59°C (lit.)
Boiling Point 198.2±13.0°C at 760 mmHg
Density 1.0±0.1 g/cm³
Flash Point 92.3±10.5°C
Refractive Index 1.452
Solubility Soluble in water and organic solvents
Purity ≥98%
Application Used as an intermediate in organic synthesis, particularly in the solid-phase synthesis of secondary amines. It is also employed in the preparation of various compounds such as N-tert-butoxycarbonyl-4-hydroxymethyl piperidine, desferrioxamine B (DFO) containing third generation triazine dendrimer, and others.
Safety Information May cause skin and eye irritation. Handle with appropriate personal protective equipment. Store in a cool, dry place away from heat, sparks, and open flames. Keep away from oxidizing agents. Follow relevant safety regulations and instructions when using this chemical.