4-Nitro-3-(Trifluoromethyl)Aniline CAS No. 393-11-3

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Introduction

Product Name

4-Nitro-3-(Trifluoromethyl)Aniline

4-Multiple Names

Nitro-3-(Trifluoromethyl)Aniline;

5-Amino-2-Nitrobenzotrifluoride;

4-Nitro-3-Trifluoromethyl aniline;

N-[4-nitro-3-(Trifluoromethyl)Phenyl]acetamide

CAS No. 393-11-3

EC No. 206-884-6

MF No. C7H5F3N2O2

MW No. 248.1587

5-Amino-2-nitrotrifluoromethylbenzene is an organic intermediate, which can be prepared from m-chlorotrifluoromethylbenzene in two steps. It can be used to prepare medicine and optical waveguide material intermediate 4-bromo-2-nitrotrifluoromethylbenzene and non-steroidal antiandrogen drug flutamide.

Advantage of 4-Nitro-3-(Trifluoromethyl)Aniline CAS No. 393-11-3

Soluble in water and ethanol, soluble in ether

It is widely used

Convenient storage

 

Aspect Details
Chemical Name 4-Nitro-3-(Trifluoromethyl)Aniline
Aliases 5-Amino-2-nitrobenzotrifluoride, 3-Trifluoromethyl-4-nitroaniline, 4-Nitro-α,α,α-trifluoro-m-toluidine
CAS Number 393-11-3
EINECS Number 206-884-6
Molecular Formula C₇H₅F₃N₂O₂
Molecular Weight 206.12 g/mol
Physical State Yellow crystalline solid
Melting Point 125-129°C
Boiling Point 326.4°C at 760 mmHg
Density 1.503 g/cm³
Solubility Insoluble in water; soluble in organic solvents like ethanol and dichloromethane
Applications – Pharmaceutical Intermediates: Serves as a key precursor in the synthesis of drugs targeting CNS disorders and anti-inflammatory agents.
– Agrochemicals: Utilized in the development of herbicides and insecticides.
– Dyes & Pigments: Acts as a chromophore in the production of azo dyes and fluorescent pigments.
– Materials Science: Explored for use in liquid crystal displays and non-linear optical materials.
Safety Precautions Classified as a hazardous substance (Xn, Harmful). Handle with appropriate PPE, including gloves, goggles, and lab coats. Store in tightly sealed containers away from heat, sparks, and incompatible materials.

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