
4-methoxyphenylboronic acid
We are a manufacturer based in China. We specialize in providing high-quality 4-methoxyphenylboronic acid for industrial clients across various sectors. Whether you need chemicals consultation or technical support, our team is here to help.
Category:Semiconductor Display Materials MOQ:100KG Shipped directly from China
Introduction
4-Methoxyphenylboronic acid is a versatile organoboron compound with a methoxy substituent at the 4-position of the phenyl ring and a boronic acid group. This compound is widely used in organic synthesis, material science, and pharmaceutical research due to its unique reactivity and structural properties.
Key Properties
Property | Details |
---|---|
IUPAC Name | 4-Methoxyphenylboronic acid |
CAS Number | 5720-07-0 |
Molecular Formula | C₇H₉BO₃ |
Molecular Weight | 151.96 g/mol |
Category | Phenylboronic acid derivative, Pharmaceutical intermediate |
Appearance | White to off-white crystalline powder |
Boiling Point | ~306.8°C |
Melting Point | 204-206°C |
Density | ~1.17 g/cm³ |
Storage Conditions | Sealed, in a cool, dry place |
Synthesis Method | Various methods including oxidation and coupling reactions |
Applications | Suzuki coupling reactions, Drug synthesis, Material science |
Synthesis
4-Methoxyphenylboronic acid can be synthesized through various methods. One approach involves the oxidation of 2.5-dibromothiophene followed by a coupling reaction with 4-methoxyphenylboronic acid in the presence of a palladium catalyst. Another method utilizes nickel phosphine complexes as catalysts to facilitate a one-step reaction between 1.3.5-triazine and 4-methoxyphenylboronic acid, yielding 2.4-dichloro-6-(4-methoxyphenyl)-1.3.5-triazine.
Applications
In organic synthesis, 4-Methoxyphenylboronic acid is a crucial building block for preparing complex molecules, especially those requiring defined stereochemistry and functionality. It is widely used in Suzuki coupling reactions, which are vital for forming carbon-carbon bonds in organic synthesis.
The compound is also used in the synthesis of biologically active molecules, such as lactate dehydrogenase inhibitors and nitro-phenoxybenzoic acid derivatives. Additionally, it serves as a modulator of survival motor neuron protein.
In material science, 4-Methoxyphenylboronic acid is used as an intermediate in the synthesis of liquid crystal materials, highlighting its potential in advanced material applications.
Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.
20+ years export experience. If you're ready to take the next step or Request Free Samples, Leave your message below and we’ll reply soon.