4-Hydroxycyclohexanone ethylene glycol acetal
Pharmaceutical Materials 2025-03-20
CAS.No：22428-87-1
Appearance: transparent colorless liquid
Molecular Formula:C8H14O3
Purity: GC ≥98.0%
Molecular weight:158.20
Capacity:20 tons/month
Application: Pharmaceutical intermediates
| Property | Details |
|---|---|
| Molecular Formula | C10H18O4 |
| Molecular Weight | 202.25 g/mol |
| Appearance | White to off-white crystalline solid or powder |
| Purity | Typically ≥95% |
| Melting Point | Data may vary; generally in the range of 120-140 °C |
| Boiling Point | Predicted to be above 250 °C at 760 mmHg |
| Density | Approximately 1.1-1.2 g/cm³ (Predicted) |
| Solubility | Soluble in organic solvents such as ethanol, methanol, and DMSO; slightly soluble in water |
| Applications | Organic synthesis, protective groups, pharmaceuticals, and materials science |
| Safety Considerations | Handle with care; avoid contact with skin and eyes; store in a cool, dry place away from moisture and oxidizers |
| Suppliers | Available from specialized chemical suppliers |
Applications
4-Hydroxycyclohexanone ethylene glycol acetal is a useful compound in organic synthesis, particularly as a protective group for both carbonyl and hydroxyl functionalities. Its acetal structure provides a stable and easily removable protecting group, allowing for selective reactions on other functional groups present in a molecule. This makes it valuable in multi-step synthetic routes where the temporary masking of carbonyl and hydroxyl groups is necessary.
In pharmaceuticals, 4-Hydroxycyclohexanone ethylene glycol acetal can be used in the synthesis of drug intermediates, contributing to the development of new therapeutic agents. Additionally, it finds applications in materials science, where its unique structure can be utilized in the design of new polymers and functional materials. Its solubility in organic solvents facilitates its use in various synthetic methodologies, while its stability under appropriate storage conditions ensures its reliability in research and industrial applications.
