4-Ethoxycarbonyl-3-ethoxyphenylacetic acid Cas:99469-99-5
Pharmaceutical Materials 2025-03-02
4-Ethoxycarbonyl-3-ethoxyphenylacetic acid, also known as 4-Ethoxycaybonyl-3-ethoxyphenyiaceticacid, is a versatile chemical compound with the CAS number 99469-99-5. This compound is characterized by its white to off-white crystalline powder appearance and its unique chemical structure, featuring an ethoxycarbonyl and ethoxy substitution on a phenylacetic acid backbone.
It is primarily used as an intermediate in the synthesis of the antidiabetic drug repaglinide, a meglitinide insulin secretagogue. The compound exhibits good solubility in organic solvents such as methanol and chloroform, and it should be stored under controlled conditions to maintain its stability.
| Compound Information | Details |
|---|---|
| Compound Name | 4-Ethoxycarbonyl-3-ethoxyphenylacetic acid |
| CAS Number | 99469-99-5 |
| Molecular Formula | C13H16O5 |
| Molecular Weight | 252.26 g/mol |
| Appearance | White to off-white crystalline powder |
| Melting Point | 78-80°C |
| Boiling Point | 414.8°C at 760 mmHg |
| Density | 1.191 g/cm³ |
| Solubility | Slightly soluble in chloroform and methanol |
| Application | Intermediate in the synthesis of repaglinide |
| Storage Conditions | Store in a cool, dry place, away from light and moisture. |
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