4-Ethoxycarbonyl-3-ethoxyphenylacetic acid Cas:99469-99-5

Pharmaceutical Materials 2025-03-02

4-Ethoxycarbonyl-3-ethoxyphenylacetic acid, also known as 4-Ethoxycaybonyl-3-ethoxyphenyiaceticacid, is a versatile chemical compound with the CAS number 99469-99-5. This compound is characterized by its white to off-white crystalline powder appearance and its unique chemical structure, featuring an ethoxycarbonyl and ethoxy substitution on a phenylacetic acid backbone.

It is primarily used as an intermediate in the synthesis of the antidiabetic drug repaglinide, a meglitinide insulin secretagogue. The compound exhibits good solubility in organic solvents such as methanol and chloroform, and it should be stored under controlled conditions to maintain its stability.

Compound Information Details
Compound Name 4-Ethoxycarbonyl-3-ethoxyphenylacetic acid
CAS Number 99469-99-5
Molecular Formula C13H16O5
Molecular Weight 252.26 g/mol
Appearance White to off-white crystalline powder
Melting Point 78-80°C
Boiling Point 414.8°C at 760 mmHg
Density 1.191 g/cm³
Solubility Slightly soluble in chloroform and methanol
Application Intermediate in the synthesis of repaglinide
Storage Conditions Store in a cool, dry place, away from light and moisture.

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