4-Dimethylaminopyridine CAS Number: 1122-58-3
Pharmaceutical Materials 2025-03-02
Chemical Name: 4-Dimethylaminopyridine
CAS Number: 1122-58-3
Molecular Formula: C7H10N2
Molecular Weight: 122.17 g/mol
Appearance: White crystalline powder
Usage: Widely used as a highly effective nucleophilic catalyst in various organic reactions.
4-Dimethylaminopyridine (DMAP) is an organic compound with the chemical formula C7H10N2, primarily recognized for its role as a potent catalyst in organic synthesis. It exists as a white to yellow crystalline powder that is highly soluble in various organic solvents such as ether and acetone. DMAP is extensively used to accelerate esterification, ester exchange, and condensation reactions. Its applications span across the pharmaceutical, dye, and polymer industries, making it a valuable chemical in the industrial sector. The compound is typically synthesized through the N-methylation of pyridine using electrophilic reagents and bases under mild reaction conditions.
| Property | Value |
|---|---|
| Chemical Formula | C7H10N2 |
| CAS Number | 1122-58-3 |
| Physical Properties | – |
| Appearance | White to yellow crystalline powder |
| Density | 1.0±0.1 g/cm³ |
| Melting Point | 108-113°C |
| Boiling Point | 162°C (50 mmHg) |
| Chemical Properties | – |
| Molecular Weight | 122.17 g/mol |
| Solubility | Soluble in organic solvents like ether, acetone |
| pH (Aqueous Solution) | Basic due to pyridine nitrogen |
| Flash Point | 110°C |
| LogP | 1.34 |
| Vapor Pressure | 0.4±0.4 mmHg at 25°C |
,Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.
