4-Chloro-2,6-diaminopyrimidine CAS No.: 156-83-2
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Category：Pharmaceutical Materials Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
4-Chloro-2,6-diaminopyrimidine, also known as 2,4-diamino-6-chloropyrimidine, is a key intermediate in pharmaceutical and organic synthesis. With a molecular formula of C₄H₅ClN₄ and a molecular weight of 144.56 g/mol, it exhibits stability at room temperature and is soluble in water and polar organic solvents. This compound is widely utilized in the production of Minoxidil (Rogaine®), a vasodilator for treating hair loss, and as a building block for synthesizing nucleoside analogs and antiviral agents. Its synthesis typically involves chlorination of 2,6-diaminopyrimidine or nucleophilic substitution reactions. Beyond pharmaceuticals, it serves as a reagent in analytical chemistry for detecting triazine compounds via GC-MS. Its versatility, coupled with ease of handling, makes it a valuable component in both industrial and research settings.
Usage： Used as an intermediate of the drug Minoxidil, also used in organically synthesized compounds.
Packaging and Shipping： 25KG/drum or as per buyer requirements.
Storage: Storage in ventilated low temperature dry warehouse; separately from oxidants and food additives.
| IUPAC Name | 4-Chloro-2,6-diaminopyrimidine |
| Other Names | 2,4-Diamino-6-chloropyrimidine, Minoxidil EP Impurity B |
| CAS Number | 156-83-2 |
| Molecular Formula | C₄H₅ClN₄ |
| Molecular Weight | 144.56 g/mol |
| Appearance | White to pale yellow crystalline solid |
| Melting Point | 199-202 °C |
| Boiling Point | 199-202 °C |
| Solubility | Slightly soluble in water |
| Uses | Organic synthesis, pharmaceutical intermediate |
| Safety Information | Potentially irritating; handle with care. Avoid contact with skin and eyes. |
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