4-Bromophenyl Isocyanate
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Category：Chemical Additives Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
4-Bromophenyl Isocyanate
Chemical Formula: C₇H₄BrNO
Structure: Phenyl ring with a bromine atom at the para position (4-position) and an isocyanate group (-N=C=O).
Physical Form: Colorless to pale yellow liquid or low-melting solid.
Properties
- Reactivity:
- Isocyanate group reacts with nucleophiles (amines, alcohols, water) to form urethanes, ureas, and derivatives.
- Solubility:
- Soluble in dichloromethane, toluene, THF; reacts with water.
Applications
- Organic Synthesis:
- Building block for pharmaceuticals, agrochemicals, and polymers.
- Urea/Urethane Production:
- Reacts with amines → ureas; reacts with alcohols → urethanes.
- Polymer Chemistry:
- Crosslinking agent for polymers and resins.
Safety Considerations
- Toxicity: Toxic and a respiratory irritant.
- Moisture Sensitivity: Degrades in presence of water; handle under inert conditions (e.g., dry N₂ atmosphere).
- Storage: Seal tightly, protect from humidity.
Summary:
4-Bromophenyl isocyanate’s reactive isocyanate group and bromine substitution make it a key reagent for synthesizing ureas, urethanes, and polymers. Its utility in pharmaceuticals and materials science is tempered by strict safety protocols due to toxicity and moisture sensitivity.
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