Pharmaceutical Materials

4-Bromo-2-fluorobenzonitrile (CAS No. 105942-08-3) is a vital intermediate in organic synthesis, widely utilized in pharmaceuticals, agrochemicals, and advanced materials. Its structure features a bromine atom and a fluorine atom on a benzene ring, combined with a nitrile functional group, enabling diverse reactivity pathways. The bromine and fluorine substituents facilitate selective functionalization reactions, such as cross-coupling and nucleophilic aromatic substitution, while the nitrile group can be hydrolyzed to carboxylic acids or reduced to amines. This compound is commonly employed in the synthesis of fluorinated pharmaceuticals, including antivirals and anticancer agents, due to its ability to enhance metabolic stability and bioavailability. Its industrial applications also extend to the production of liquid crystals and specialty polymers. Typically available as a white to light brown crystalline powder, it exhibits a melting point of 69-72°C and a boiling point of 238-239°C, with moderate density and insolubility in water.

4-Bromo-2-fluorobenzonitrile Usage： Used as intermediates of pharmaceutical and liquid crystal materials.

Packaging and Shipping： 25KG/drum.

Storage: Keep container sealed and store in an ventilated, low temperature, dry warehouse, separate from foods and oxidizing agents.

Name	2-Fluoro-4-bromobenzonitrile
Synonyms	2-Fluoro-4-bromobenzonitrile 2-FLUORO-4-BROMOBENZONITRILE 4-Bromo-2-fluorobenzonitrile 4-BROMO-2-FLUOROBENZONITRILE 4-cyano-3-fluoro-1-broMobenzene 1-Fluoro-2-cyano-5-bromobenzene 4-(bromomethyl)-3-fluorobenzonitrile
CAS	105942-08-3
InChI	InChI=1/C8H5BrFN/c9-4-7-2-1-6(5-11)3-8(7)10/h1-3H,4H2
InChIKey	HGXWRDPQFZKOLZ-UHFFFAOYSA-N

Molecular Formula	C7H3BrFN
Molar Mass	200.01
Density	1.7286 (rough estimate)
Melting Point	69-72 °C
Boling Point	238-239°C
Flash Point	238-239°C
Water Solubility	insoluble
Vapor Presure	0.00481mmHg at 25°C
Appearance	Crystalline Powder or Chunks
Color	White to light brown
BRN	4231143
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.5320 (estimate)
Physical and Chemical Properties	Melting Point: 249 – 254 ℃

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