Pharmaceutical Materials

4-Bromo-2-fluoroanisole, with the CAS number 2357-52-0, is a significant organic compound utilized in pharmaceuticals and agrochemicals as a key intermediate. Its molecular formula, C₇H₆BrFO, and molecular weight of 205.02 g/mol define its chemical structure. This compound exhibits a boiling point of 84°C at 7 mmHg and a density of 1.59 g/cm³, making it suitable for reactions requiring low-temperature conditions. Its refractive index (n₂₀/D 1.545) and insolubility in water further enhance its utility in organic synthesis. As a hazardous substance (Xi), it necessitates careful handling under inert gas and sealed storage at 2–8°C to prevent degradation. Its synthesis efficiency has been reported at 65%, making it a valuable precursor in the production of fluorinated aromatics.

Usage： Used in the synthesis of pharmaceutical intermediates.

Packaging and Shipping： 200L/drum or as per buyer’s requirements.

Storage: Storage in ventilated low temperature dry warehouse; Keep container closed and separately from open flame and heat source.

Name	4-Bromo-2-fluoroanisole
Synonyms	2-fluoro-4-bromoanisole 4-Bromo-2-fluoroanisole 2-FLUORO-4-BROMOANISOLE 4-BROMO-2-FLUOROANISOLE 4-Bromo-2-Fluoromethoxybenzene 1-BROMO-3-FLUORO-4-METHOXYBENZENE 4-Bromo-2-fluoro-1-methoxybenzene Benzene, 4-bromo-2-fluoro-1-methoxy-
CAS	2357-52-0
EINECS	219-096-2
InChI	InChI=1/C7H6BrFO/c1-10-7-3-2-5(8)4-6(7)9/h2-4H,1H3

Molecular Formula	C7H6BrFO
Molar Mass	205.02
Density	1.59 g/mL at 25 °C (lit.)
Melting Point	16 °C
Boling Point	84 °C/7 mmHg (lit.)
Flash Point	209°F
Water Solubility	insoluble
Appearance	clear liquid
Specific Gravity	1.590
Color	Colorless to Light yellow
BRN	3240714
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	n20/D 1.545(lit.)
Physical and Chemical Properties	Colorless transparent liquid. The relative density was 1.590.

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