4-Aminoveratrole

Pharmaceutical Materials 2025-03-02

CAS Number: 6315-89-5

Molecular Formula: C8H11NO2

Molecular Weight: 153.18 g/mol

Appearance: Brown crystalline powder or grayish white powder

Melting Point: 85-89°C

Boiling Point: 296.3°C (at 760 mmHg)

Usage: Used as an intermediate in medicine and dye production.

 

Aspect Details
Name 4-Aminoveratrole
Common Synonyms 1-Amino-2.3-dimethoxybenzene, 4-Amino-1.2-dimethoxybenzene
CAS No. 635-90-3
Molecular Formula C₈H₁₁NO₂
Molecular Weight 153.18 g/mol
Physical Properties
  • Appearance: Pale yellow to brown crystalline solid
  • Melting Point: 83-85 °C
  • Solubility: Soluble in organic solvents (e.g., ethanol, DMSO); slightly soluble in water
  • Density: Approx. 1.17 g/cm³
Chemical Properties
  • Contains an amino group (-NH₂) and two methoxy groups (-OCH₃) on a benzene ring
  • Exhibits basicity due to the amino group
  • Undergoes typical aromatic substitution reactions (e.g., nitration, acylation)
  • Stable under normal conditions but may oxidize in air
Applications
  • Used as an intermediate in pharmaceutical synthesis (e.g., analgesics and anti-inflammatory drugs)
  • Employed in agrochemicals as a bioactive scaffold
  • Utilized in dye chemistry for azo dye production
Safety Information
  • GHS Hazards: H302 (harmful if swallowed), H315 (causes skin irritation)
  • Precautionary Measures: Avoid inhalation and contact with eyes; use PPE
  • Storage: Keep in a tightly sealed container in a cool, dry place

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