4-Aminobiphenyl
Pharmaceutical Materials 2025-03-02
CAS Number: 92-67-1
Molecular Formula: C12H11N
Molecular Weight: 169.22
Melting Point: 52-54°C
Boiling Point: 191°C at 15 mmHg
Appearance: Colorless to tan crystalline solid
Usage: Pharmaceutical intermediates and analytical reference standard.
| Property | Details |
|---|---|
| Chemical Name | 4-Aminobiphenyl |
| Synonyms | p-Aminobiphenyl, 4-Biphenylamine, 4-Phenylaniline |
| CAS Number | 92-67-1 |
| EINECS Number | 202-177-1 |
| Molecular Formula | C₁₂H₁₁N |
| Molecular Weight | 169.22 g/mol |
| Physical State | White to light gray crystalline solid |
| Melting Point | 127–129°C |
| Boiling Point | 352°C |
| Solubility | Slightly soluble in water; soluble in organic solvents like ethanol and ether |
| Applications | – Historically used in the production of azo dyes and rubber chemicals. – Served as an intermediate in organic synthesis for pharmaceuticals and agrochemicals. – Due to its carcinogenic properties, its use is now highly restricted or banned in many regions. |
| Health & Safety | – Classified as a human carcinogen (Group 1) by the International Agency for Research on Cancer (IARC). – Exposure may lead to bladder cancer and other malignancies. – Handle with extreme caution using appropriate personal protective equipment (PPE). |
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