Pharmaceutical Materials

(3S) -3- [4- [(2-chloro-5-iodophenyl) methyl] phenoxy] tetrahydrofuran, also known as 3- [4- [(2-Chloro-5-iodophenyl) methyl] phenyl] tetrahydrofuran, is an organic compound.

Nature:

(3S) -3- [4- [(2-chloro-5-iodophenyl) methyl] phenoxy] tetrahydrofuran is a solid compound. Its appearance is white crystalline powder. This compound is stable at room temperature, but prolonged exposure to sunlight should be avoided. It is easily soluble in organic solvents.

Purpose:

Manufacturing method:

The preparation method of (3S) -3- [4- [(2-chloro-5-iodophenyl) methyl] phenoxy] tetrahydrofuran can be achieved through chemical synthesis. A common method is to react iodobenzene and benzyl alcohol in dichloromethane with tetrahydrofuran in the presence of zinc iodide to obtain the target product.

Security information:

Corresponding safety measures need to be taken when using and handling (3S) -3- [4- [(2-chloro-5-iodophenyl) methyl] phenoxy] tetrahydrofuran. It may cause irritation and eye damage to the human body, and should be avoided from inhalation, contact with skin and eyes. Wear protective gloves, goggles, and protective clothing during operation. This compound should be stored in a dry, cool place, away from sources of fire and oxidants.

Name	(3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydro-furan
Synonyms	EMpagliflozin iMpurity C (3S)-3-{4-[(2-chloro-5-iodophenyl)methyl]phenoxy}oxolane (S)-3-(4-(2-chloro-5-iodobenzyl)phenoxy)-tetrahydrofuran (3S)-3-[4-(2-chloro-5-iodobenzyl)-phenoxy]-tetrahydrofuran (S)-3-(4-(2-chloro-5-fluorobenzyl)phenoxy)-tetrahydrofuran (S)-4-iodo-1-chloro-2-(4-tetrahydrofuran-3-yloxy-benzyl)-benzene (3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydro-furan Furan, 3-[4-[(2-chloro-5-iodophenyl)methyl]phenoxy]tetrahydro-, (3S)-
CAS	915095-94-2
EINECS	619-599-0

Molecular Formula	C17H16ClIO2
Molar Mass	414.67
Density	1.578±0.06 g/cm3 (20 ºC 760 Torr)
Boling Point	476.0±45.0 °C(Predicted)
Storage Condition	2-8°C(protect from light)

Reference Information

Use

(3S)-3-[4-[(2-chloro-5-iodophenyl) methyl] phenoxy] tetrahydrofuran can be used as a reactant/reagent for the preparation of C- aryl D-oligofuranoside compounds, and can be used as a reference compound for the quality control of glitfluzine drugs. (3S)-3-[4-[(2-chloro-5-iodophenyl)] methyl] phenoxy] tetrahydrofuran can be used as a reactant/reagent for the preparation of C- aryl D-glucoside compounds, and can be used as a control compound for the quality control of glibenclamin drugs.

Application

(3S)-3-[4-[(2-chloro-5-iodophenyl) methyl] phenoxy] tetrahydrofuran is an intermediate in organic synthesis and pharmaceutical intermediates, which can be used in laboratory research and development process and chemical production process, mainly as an intermediate of API.

,Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.

If you're ready to take the next step, Leave your message below and we’ll reply soon. 20+ years of chemical manufacturing & export experience, a partner you can trust.