(3S)-3-[4-[(5-Iodo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran
Category：Pharmaceutical Materials
Introduction
(3S) -3- [4- [(2-chloro-5-iodophenyl) methyl] phenoxy] tetrahydrofuran, also known as 3- [4- [(2-Chloro-5-iodophenyl) methyl] phenyl] tetrahydrofuran, is an organic compound.
nature:
(3S) -3- [4- [(2-chloro-5-iodophenyl) methyl] phenoxy] tetrahydrofuran is a solid compound. Its appearance is white crystalline powder. This compound is stable at room temperature, but prolonged exposure to sunlight should be avoided. It is easily soluble in organic solvents.
Purpose:
Manufacturing method:
The preparation method of (3S) -3- [4- [(2-chloro-5-iodophenyl) methyl] phenoxy] tetrahydrofuran can be achieved through chemical synthesis. A common method is to react iodobenzene and benzyl alcohol in dichloromethane with tetrahydrofuran in the presence of zinc iodide to obtain the target product.
Security information:
Corresponding safety measures need to be taken when using and handling (3S) -3- [4- [(2-chloro-5-iodophenyl) methyl] phenoxy] tetrahydrofuran. It may cause irritation and eye damage to the human body, and should be avoided from inhalation, contact with skin and eyes. Wear protective gloves, goggles, and protective clothing during operation. This compound should be stored in a dry, cool place, away from sources of fire and oxidants.
| Name | (3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydro-furan |
| Synonyms | EMpagliflozin iMpurity C (3S)-3-{4-[(2-chloro-5-iodophenyl)methyl]phenoxy}oxolane (S)-3-(4-(2-chloro-5-iodobenzyl)phenoxy)-tetrahydrofuran (3S)-3-[4-(2-chloro-5-iodobenzyl)-phenoxy]-tetrahydrofuran (S)-3-(4-(2-chloro-5-fluorobenzyl)phenoxy)-tetrahydrofuran (S)-4-iodo-1-chloro-2-(4-tetrahydrofuran-3-yloxy-benzyl)-benzene (3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydro-furan Furan, 3-[4-[(2-chloro-5-iodophenyl)methyl]phenoxy]tetrahydro-, (3S)- |
| CAS | 915095-94-2 |
| EINECS | 619-599-0 |
| Molecular Formula | C17H16ClIO2 |
| Molar Mass | 414.67 |
| Density | 1.578±0.06 g/cm3 (20 ºC 760 Torr) |
| Boling Point | 476.0±45.0 °C(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
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