(3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran
Pharmaceutical Materials 2025-03-02
(3S) -3- [4- [(5-bromo-2-chlorophenyl) methyl] phenoxy] tetrahydrofuran is an organic compound.
nature:
(3S) -3- [4- [(5-bromo-2-chlorophenyl) methyl] phenoxy] tetrahydrofuran is a colorless to pale yellow solid that is soluble in some organic solvents such as chloroform and dichloromethane.
Purpose:
Manufacturing method:
The preparation method of (3S) -3- [4- [(5-bromo-2-chlorophenyl) methyl] phenoxy] tetrahydrofuran is relatively complex. A common synthesis method is to first synthesize 4- [(5-bromo-2-chlorophenyl) methyl] phenol through chemical reaction, and then perform unconventional cycloalkylation reaction with tetrahydrofuran to obtain the target product.
Security information:
Safety information for (3S) -3- [4- [(5-bromo-2-chlorophenyl) methyl] phenoxy] tetrahydrofuran: More specific experimental data is needed to determine, such as toxicity testing and safety operation guidelines. When used in the laboratory, it is necessary to follow standard chemical operating procedures and personal protective measures.
| Name | (3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydro-furan |
| Synonyms | 915085-89-5 Empagliflozin-7 EMpagliflozin int3 Empagliflozin Bromo Impurity 3-[4-[(5-broMo-2-chlorophenyl)Methyl]phenoxy]tetrahydro- (3S)-3-(4-(5-Bromo-2-chlorobenzyl)phenoxy)tetrahydro-furan (3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran (S)-4-bromo-1-chloro-2-(4-tetrahydrofuran-3-yloxy-benzyl)-benzene (3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydro-furan (3S)-3-[4-[(5-bromo-2-chlorophenyl)methyl]phenoxy]oxolane 915095-89-5 |
| CAS | 915095-89-5 |
| EINECS | 1592732-453-0 |
| Molecular Formula | C17H16BrClO2 |
| Molar Mass | 367.66 |
| Density | 1.431±0.06 g/cm3 (20 ºC 760 Torr) |
| Melting Point | 49-51°C |
| Boling Point | 459.1±45.0 °C(Predicted) |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Appearance | Solid |
| Color | White to Off-White |
| Storage Condition | Sealed in dry,Room Temperature |
Reference Information
| use | (3S)-3-[4-[(5-bromo -2-chlorophenyl) methyl] phenoxy] tetrahydrofuran is used as a reactant, and AlCl3-promoted silane reduction β-pyropyranoside is used to effectively synthesize SGLT-2 egliflozin inhibitors. Epalijing intermediate |
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