3,5-Difluoropicolinic acid
Pharmaceutical Materials 2025-03-02
CAS Number: 745784-04-7
Molecular Formula: C6H3F2NO2
Molecular Weight: 159.09 g/mol
Appearance: Off-white solid
Melting Point: 202-204 °C
Density: 1.535 g/cm3
Usage: Used as an intermediate in organic synthesis and pharmaceutical industry.
| Aspect | Details |
|---|---|
| Name | 3.5-Difluoropicolinic Acid |
| CAS Number | 745784-04-7 |
| Chemical Formula | C₆H₃F₂NO₂ |
| Molecular Weight | 159.09 g/mol |
| Physical Appearance | Off-white powder |
| Melting Point | 202–204°C |
| Boiling Point | 240.6 ± 35.0°C (predicted) |
| Density | 1.535 ± 0.06 g/cm³ (predicted) |
| Solubility | Soluble in organic solvents like benzene and toluene; insoluble in water. |
| Reactivity | Acts as a key intermediate in pharmaceutical synthesis; participates in amidation and cross-coupling reactions. |
| Applications | – Pharmaceuticals: Synthesis of hormone analogs and bioactive molecules. |
| – Materials Science: Precursor for advanced polymers and functionalized materials. | |
| – Agrochemicals: Intermediate in pesticide and herbicide formulations. | |
| Safety Information | – Hazards: Irritant (Xi; R36/37/38); wear PPE during handling. |
| – Storage: Keep in a sealed, dry container at room temperature, away from oxidizing agents. |
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