3,5-Difluoropicolinic acid

Pharmaceutical Materials 2025-03-02

CAS Number: 745784-04-7

Molecular Formula: C6H3F2NO2

Molecular Weight: 159.09 g/mol

Appearance: Off-white solid

Melting Point: 202-204 °C

Density: 1.535 g/cm3

Usage: Used as an intermediate in organic synthesis and pharmaceutical industry.

 

Aspect Details
Name 3.5-Difluoropicolinic Acid
CAS Number 745784-04-7
Chemical Formula C₆H₃F₂NO₂
Molecular Weight 159.09 g/mol
Physical Appearance Off-white powder
Melting Point 202–204°C
Boiling Point 240.6 ± 35.0°C (predicted)
Density 1.535 ± 0.06 g/cm³ (predicted)
Solubility Soluble in organic solvents like benzene and toluene; insoluble in water.
Reactivity Acts as a key intermediate in pharmaceutical synthesis; participates in amidation and cross-coupling reactions.
Applications – Pharmaceuticals: Synthesis of hormone analogs and bioactive molecules.
– Materials Science: Precursor for advanced polymers and functionalized materials.
– Agrochemicals: Intermediate in pesticide and herbicide formulations.
Safety Information – Hazards: Irritant (Xi; R36/37/38); wear PPE during handling.
– Storage: Keep in a sealed, dry container at room temperature, away from oxidizing agents.

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