3,5-Difluorophenol
Category：Pharmaceutical Materials
Introduction
CAS.No：2713-34-0
| Property | Details |
|---|---|
| CAS Number | 28123-10-0 |
| Molecular Formula | C6H4F2O |
| Molecular Weight | 130.09 g/mol |
| Appearance | White to off-white crystalline solid or powder |
| Purity | Typically ≥98% |
| Melting Point | 49-52 °C |
| Boiling Point | 158-160 °C (at 760 mmHg) |
| Density | 1.44 g/cm³ |
| Solubility | Soluble in ethanol, ether, and acetone; slightly soluble in water |
| Applications | Organic synthesis, pharmaceuticals, agrochemicals, and materials science |
| Safety Considerations | Handle with care; avoid contact with skin and eyes; store in a cool, dry place away from oxidizers and strong acids |
| Suppliers | Available from various chemical suppliers globally |
Applications
3.5-Difluorophenol is a versatile compound widely used in organic synthesis. Its difluorinated phenol structure provides unique reactivity, making it a valuable intermediate in the synthesis of various fluorinated compounds. In pharmaceuticals, 3.5-Difluorophenol is utilized in the production of drugs with enhanced metabolic stability and bioavailability, contributing to the development of new therapeutic agents.
In agrochemicals, it serves as a building block for the synthesis of herbicides and pesticides, offering improved efficacy and environmental safety. Additionally, 3.5-Difluorophenol finds applications in materials science, where its fluorinated nature can be exploited to create polymers and materials with tailored properties. Its solubility in organic solvents facilitates its use in various synthetic methodologies, while its stability under appropriate storage conditions ensures its reliability in research and industrial applications.
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