3,5-difluoro-4- [(3,4,5-trifluorophenyl) difluoromethoxy] -4 ‘- propylbiphenyl
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Category：Semiconductor Display Materials Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
| Section | Details |
|---|---|
| Chemical Structure | Name: 3.5-Difluoro-4-[(3.4.5-trifluorophenyl)difluoromethoxy]-4′-propylbiphenyl Formula: C₂₂H₁₅F₇O CAS No.: 337456-92-5 Molecular Weight: 428.34 g/mol Appearance: White/off-white powder. |
| Physical Properties | Melting Point/Boiling Point: Data not specified (typically high due to fluorination). Solubility: Likely low in polar solvents due to fluorinated hydrophobic structure. Density: Estimated ~1.3-1.4 g/cm³ (common for fluorinated aromatics). |
| Chemical Properties | Stability: Fluorine substitution enhances thermal and chemical stability. Reactivity: Reduced nucleophilicity due to electron-withdrawing fluorine atoms; may undergo electrophilic aromatic substitution under harsh conditions. |
| Synthesis Methods | Likely involves multi-step coupling reactions (e.g., Suzuki-Miyaura cross-coupling or nucleophilic substitution) to link fluorinated aromatic rings and install the difluoromethoxy group. Specific protocols require further literature review. |
| Applications | Pharmaceuticals: Serves as an intermediate for synthesizing fluorinated drugs (e.g., antifungals, anti-inflammatories). Materials Science: Potential use in liquid crystals or electronic materials due to fluorination-induced anisotropic properties. Research: Model compound to study fluorine effects on molecular conformation, metabolic stability, and membrane permeability. |
| Availability | Commercially available from suppliers like TCI, Aladdin, and others in purities ≥98%, with packaging from 250 mg to 100 g. |
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