3,4-Dihydro-2H-pyran CAS No.:110-87-2

Pharmaceutical Materials 2025-03-03

3,4-Dihydro-2H-pyran (DHP) is a versatile cyclic ether widely used in organic synthesis and pharmaceutical chemistry. With a molecular formula of C₅H₈O and a molecular weight of 84.12 g/mol, DHP is a colorless liquid with a boiling point of 86 °C and a melting point of -70 °C. It serves as a key protecting group for hydroxyl (-OH) functionalities, enabling selective reactions in complex molecule synthesis. DHP is stable under basic conditions but labile under acidic or Lewis acidic environments, facilitating controlled deprotection. Its reactivity extends to polymerization, hydrogenation, and oxidation, yielding derivatives such as tetrahydropyran (THP) and resin products. Additionally, DHP acts as a solvent and a reagent in the synthesis of pharmaceuticals, agrochemicals, and functional materials, demonstrating broad industrial and research applications.

Usage: Used as a pharmaceutical intermediate Pharmaceutical intermediates, used in 1,5-dichloropentane, and then can be used to synthesize heptanediamine, pimelic acid, and used to produce synthetic fibers. Widely used in OH protection reagents. Dihydropyran is chemically active, and tetrahydropyran, pentanediol, glutaric acid, valerolactone, pentadiene and resin products can be prepared through polymerization, hydrogenation, oxidation and other reactions.

Packaging and Shipping: 180kg/drum.

Storage:Stored in a dry and ventilated warehouse; keep away from sunshine; avoid fire; avoid moisture.

IUPAC Name 3,4-Dihydro-2H-pyran
Other Names 2,3-Dihydropyran, 3,4-Dihydropyran (DHP, THP)
CAS Number 110-87-2
Molecular Formula C₅H₈O
Molecular Weight 84.12 g/mol
Appearance Colorless liquid
Melting Point -70 °C
Boiling Point 86 °C
Solubility Soluble in water and ethanol, slightly soluble in chloroform
Uses Organic synthesis, pharmaceutical intermediate
Safety Information Flammable; avoid contact with skin, eyes, and inhalation of vapors. Handle with care.

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