3,4-Dihydro-2H-pyran CAS No.:110-87-2
Pharmaceutical Materials 2025-03-03
3,4-Dihydro-2H-pyran (DHP) is a versatile cyclic ether widely used in organic synthesis and pharmaceutical chemistry. With a molecular formula of C₅H₈O and a molecular weight of 84.12 g/mol, DHP is a colorless liquid with a boiling point of 86 °C and a melting point of -70 °C. It serves as a key protecting group for hydroxyl (-OH) functionalities, enabling selective reactions in complex molecule synthesis. DHP is stable under basic conditions but labile under acidic or Lewis acidic environments, facilitating controlled deprotection. Its reactivity extends to polymerization, hydrogenation, and oxidation, yielding derivatives such as tetrahydropyran (THP) and resin products. Additionally, DHP acts as a solvent and a reagent in the synthesis of pharmaceuticals, agrochemicals, and functional materials, demonstrating broad industrial and research applications.
Usage: Used as a pharmaceutical intermediate Pharmaceutical intermediates, used in 1,5-dichloropentane, and then can be used to synthesize heptanediamine, pimelic acid, and used to produce synthetic fibers. Widely used in OH protection reagents. Dihydropyran is chemically active, and tetrahydropyran, pentanediol, glutaric acid, valerolactone, pentadiene and resin products can be prepared through polymerization, hydrogenation, oxidation and other reactions.
Packaging and Shipping: 180kg/drum.
Storage:Stored in a dry and ventilated warehouse; keep away from sunshine; avoid fire; avoid moisture.
| IUPAC Name | 3,4-Dihydro-2H-pyran |
| Other Names | 2,3-Dihydropyran, 3,4-Dihydropyran (DHP, THP) |
| CAS Number | 110-87-2 |
| Molecular Formula | C₅H₈O |
| Molecular Weight | 84.12 g/mol |
| Appearance | Colorless liquid |
| Melting Point | -70 °C |
| Boiling Point | 86 °C |
| Solubility | Soluble in water and ethanol, slightly soluble in chloroform |
| Uses | Organic synthesis, pharmaceutical intermediate |
| Safety Information | Flammable; avoid contact with skin, eyes, and inhalation of vapors. Handle with care. |
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