3-Pyridinecarboxaldehyde
Agrochemicals 2025-03-02
3-Pyridinecarboxaldehyde (CAS No. 500-22-1)
1. Basic Information
- IUPAC Name: Pyridine-3-carbaldehyde
- Synonyms:
- Nicotinaldehyde
- 3-Formylpyridine
- CAS Number: 500-22-1
- Molecular Formula: C₆H₅NO
- Molecular Weight: 107.11 g/mol
- Appearance: Colorless to pale yellow liquid
- Odor: Pungent, pyridine-like odor
2. Physical and Chemical Properties
| Property | Value |
|---|---|
| Boiling Point | 85–87°C (185–189°F) at 15 mmHg |
| Density | 1.13 g/cm³ (20°C) |
| Refractive Index | 1.550–1.552 (20°C) |
| Flash Point | 72°C (162°F) (closed cup) |
| Solubility | – Water: Partially soluble |
| – Organic solvents: Miscible with ethanol, ether, acetone | |
| Vapor Pressure | 0.3 mmHg at 25°C |
3. Hazards (GHS Classification)
- Health Hazards:
- Harmful if swallowed (H302)
- Causes skin irritation (H315)
- Causes serious eye irritation (H319)
- Environmental: Toxic to aquatic life (H411)
- NFPA Rating: Health 2, Flammability 2, Reactivity 1
4. Storage and Handling
- Storage:
- Keep in tightly sealed amber containers under nitrogen
- Store in a cool, dry, well-ventilated area
- Handling:
- Use nitrile gloves, safety goggles, and a fume hood
- Avoid contact with strong oxidizers
5. Applications
- Pharmaceuticals:
- Intermediate for antihypertensive drugs (e.g., nifedipine)
- Agrochemicals:
- Building block for pesticides
- Organic Synthesis:
- Precursor for Schiff bases and heterocycles
Disclaimer:
The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.
