(3-Fluoro-4 ‘- propyl – [1,1’ – biphenyl] -4-yl) boronic acid
We are a manufacturer based in China. We specialize in providing high-quality (3-Fluoro-4 ‘- propyl – [1,1’ – biphenyl] -4-yl) boronic acid for industrial clients across various sectors. Whether you need chemicals consultation or technical support, our team is here to help.
Category：Semiconductor Display Materials MOQ:100KG Shipped directly from China
Introduction
(3-Fluoro-4′-propyl-[1.1′-biphenyl]-4-yl)boronic acid is a fluorinated biphenyl boronic acid derivative with potential applications in organic synthesis and medicinal chemistry. This compound is characterized by its unique molecular structure, combining a fluorine atom at the meta position of one benzene ring and a propyl substituent on the adjacent ring. The boronic acid group is located at the para position relative to the propyl group, providing a reactive site for various coupling reactions.
Key Properties
The compound exhibits good stability under normal conditions and can be stored at room temperature. It is soluble in common organic solvents, facilitating its use in various reaction media. The presence of the fluorine atom imparts unique electronic and steric properties to the molecule, influencing its reactivity and biological activity.
Synthesis
The synthesis of (3-Fluoro-4′-propyl-[1.1′-biphenyl]-4-yl)boronic acid typically involves palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling. This method allows for the efficient construction of the biphenyl framework by coupling a fluorinated aryl halide with a propyl-substituted arylboronic acid.
Applications
In organic synthesis, this compound serves as a valuable building block for the preparation of complex molecules with defined stereochemistry and functionality. Its fluorinated biphenyl structure makes it a promising candidate for the development of novel pharmaceuticals, agrochemicals, and functional materials. The boronic acid moiety can be further transformed into other functional groups, expanding the scope of its applications.
| Property | Details |
|---|---|
| IUPAC Name | (3-Fluoro-4′-propyl-[1.1′-biphenyl]-4-yl)boronic acid |
| CAS Number | 909709-42-8 |
| Molecular Formula | C₁₅H₁₆BFO₂ |
| Molecular Weight | 258.0992 g/mol |
| Appearance | White to off-white powder |
| Density | 1.17±0.1 g/cm³ (Predicted) |
| Boiling Point | 412.5±55.0 °C (Predicted) |
| Refractive Index | 1.567 |
| Flash Point | 203.3±31.5 °C |
| Synthesis Method | Palladium-catalyzed cross-coupling reactions (e.g., Suzuki-Miyaura coupling) |
| Applications | Organic synthesis, medicinal chemistry, development of novel pharmaceuticals |
Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.
20+ years export experience. If you're ready to take the next step or Request Free Samples, Leave your message below and we’ll reply soon.
Inquiry
Factory & Shipment
