3-Chloropropyne

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Category:Agrochemicals   Own Brand:MT  /MOQ:100KG  /From China/  B2B only.

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Introduction

3-Chloropropyne (Propargyl Chloride, CAS No. 624-65-7) 


1. Basic Information

  • IUPAC Name: 3-Chloroprop-1-yne
  • Synonyms:
    • Propargyl chloride
    • Chloromethylacetylene
  • CAS Number: 624-65-7
  • Molecular Formula: C₃H₃Cl
  • Molecular Weight: 74.51 g/mol
  • Appearance: Colorless to pale yellow liquid
  • Odor: Pungent, garlic-like odor

2. Physical and Chemical Properties

Property Value
Boiling Point 57–59°C (135–138°F)
Density 1.03 g/cm³ (20°C)
Refractive Index 1.432 (20°C)
Flash Point -20°C (-4°F) (closed cup)
Solubility – Water: Slightly soluble
– Organic solvents: Miscible with ethanol, ether, acetone
Vapor Pressure 200 mmHg at 20°C

3. Chemical Structure

   Cl  
    |  
   CH≡C-CH₃

4. Hazards (GHS Classification)

  • Flammability: Highly flammable liquid (H224)
  • Health Hazards:
    • Fatal if inhaled (H330)
    • Causes severe skin burns (H314)
    • Causes serious eye damage (H318)
  • Environmental: Toxic to aquatic life (H411)
  • NFPA Rating: Health 3, Flammability 3, Reactivity 2

5. Storage and Handling

  • Storage:
    • Store in explosion-proof refrigerators (<10°C) under inert gas (N₂)
    • Keep away from heat/sparks/open flames
  • Handling:
    • Use explosion-proof equipment and chemical-resistant gloves (Viton®/butyl rubber)
    • Work in a fume hood with <25% lower explosive limit (LEL) monitoring

6. Applications

  • Organic Synthesis:
    • Alkynylation agent for C-C bond formation
    • Intermediate for pharmaceuticals (e.g., HIV protease inhibitors)
  • Polymer Industry:
    • Crosslinking agent for specialty resins
  • Agrochemicals:
    • Building block for fungicides

Disclaimer:

The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.

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