3′-Chloropropiophenone CAS No.: 34841-35-5

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Category:Pharmaceutical Materials   Own Brand:MT  /MOQ:100KG  /From China/  B2B only.

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Introduction

3′-Chloropropiophenone, also known as m-chloropropiophenone or 1-(3-chlorophenyl)propan-1-one, is a key intermediate in organic synthesis with the CAS number 34841-35-5. Its molecular formula is C₉H₉ClO, and it has a molecular weight of 168.62 g/mol. This white crystalline solid exhibits a melting point of 45–47°C and a boiling point of 124°C (14 mmHg), with limited solubility in water. It is widely used in pharmaceutical chemistry for synthesizing antidepressants like bupropion (Wellbutrin) and other bioactive compounds. Its reactivity stems from the electron-withdrawing chlorine atom and the carbonyl group, facilitating nucleophilic addition and substitution reactions. Safety precautions include avoiding exposure to strong oxidizers and using protective equipment during handling due to its irritant properties.

Usage: Mainly usedOrganic synthesis, pharmaceutical synthesis intermediates, can be used for the synthesis of wellbutrin.

Packaging and Shipping: 25KG/drum or as per buyer requirement.

Storage: Keep container sealed and store in an ventilated, low temperature, dry warehouse, separate from foods and oxidizing agents.

Name 3′-Chloropropiophenone
Synonyms MCPP
M-CHLOROPROPIOPHENONE
m-chlorophenylacetone
3′-Chloropropiophenone
beta-Chloropropiophenone
3-CHLORO-1-PHENYL-PROPANONE
2-Chloroethyl phenyl ketone
3-CHLOROPHENYL ETHYL KETONE
(3-CHLOROPHENYL)PROPAN-1-ONE
3-chloro-1-phenylpropan-1-one
3-Chloro-1-phenyl-1-propanone
1-(3-CHLOROPHENYL)-1-PROPANONE
1-(3-Chlorophenyl)-1-propanone
1-(3-chlorophenyl)propan-1-one
1-(4-chlorophenyl)propan-1-one
3-CHLOROPROPIOPHENONE M-CHLORO PROPIOPHENONE
3-Chloro-Propiophenone(M-ChloroProiophenone)
CAS 34841-35-5
EINECS 252-242-3
InChI InChI=1/C9H9ClO/c1-2-9(11)7-4-3-5-8(10)6-7/h3-6H,2H2,1H3
InChIKey PQWGFUFROKIJBO-UHFFFAOYSA-N
Molecular Formula C9H9ClO
Molar Mass 168.62
Density 1.1115 (rough estimate)
Melting Point 45-47°C(lit.)
Boling Point 124°C14mm Hg(lit.)
Flash Point >230°F
Solubility Soluble in methanol.
Vapor Presure 0.0266mmHg at 25°C
Appearance Bright yellow crystal
Color White to light yellow
Storage Condition Sealed in dry,Room Temperature
Refractive Index 1.5350 (estimate)
MDL MFCD00009925
Physical and Chemical Properties Melting point 43-47°C
boiling point 124°C (14 torr)
Use For the synthesis of the drug bupropion

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