3-Chlorophenylboronic acid

Pharmaceutical Materials 2025-03-20

CAS.No:63503-60-6

Appearance: white powder

Molecular Formula :C6H6BCIO2

Purity:HPLC≥99.5%

Molecular weight:156.37

Capacity:20 tons/month

Application:Vadostat intermediates, pharmaceutical intermediates

 

Property Details
CAS Number 63503-60-6
Molecular Formula C6H6BClO2
Molecular Weight 156.37 g/mol
Appearance White to light yellow-green crystalline powder or solid
Purity Typically ≥97%
Melting Point 185-189 °C
Boiling Point 311.4±44.0 °C at 760 mmHg (Predicted)
Density 1.3±0.1 g/cm³
Solubility Soluble in organic solvents such as N,N-dimethylformamide, methanol, and dichloromethane; slightly soluble in water
Applications Organic synthesis, Suzuki-Miyaura coupling reactions, drug discovery, biochemical research
Safety Considerations Handle with care; avoid contact with skin and eyes; store in a cool, dry place away from oxidizers
Suppliers Available from various chemical suppliers globally

Applications

3-Chlorophenylboronic acid is a versatile compound widely used in organic synthesis. It serves as a key intermediate in Suzuki-Miyaura coupling reactions, which are important for forming carbon-carbon bonds in the synthesis of complex organic molecules. Additionally, it is utilized in drug discovery and biochemical research due to its reactivity and ability to undergo various chemical transformations. Its solubility in organic solvents makes it suitable for a range of synthetic methodologies, while its stability under appropriate storage conditions ensures its reliability in research applications.