Pharmaceutical Materials

CAS No.96-24-2

Name

3-Chloro-1.2-propanediol

Synonyms

U-5897

Epibloc

Chlorohydrin

monochlorohydrin

alpha-chlorohydrin

chlorodeoxyglycerol

1-Chloro-1-deoxyglycerol

3-Chloropropylene glycol

1-Chloropropane-2.3-diol

1-chloropropane-2.3-diol

3-chloropropane-1.1-diol

1-chloro-2.3-propanediol

3-chloropropane-1.2-diol

3-Chloro-1.2-propanediol

1-chloropropane-1.1-diol

2-Propanediol,3-chloro-1

Glycerol monochlorohydrin

1.2-Propanediol, 3-dichloro-

2.3-dihydroxypropyl chloride

1.2-Dihydroxy-3-chloropropane

(RS)-3-Chloro-1.2-propanediol

3-Chloro-1.2-dihydroxypropane

1-chloro-2.3-dihydroxypropane

,’-Dihydroxy-iso-propylchloride

Glycerol alpha-monochlorohydrin

glycerine alpha-monochlorohydrin

beta,beta’-dihydroxyisopropylchloride

Reference Information

category    toxic substances

toxicity grade    high toxicity

Acute toxicity    oral-rat LD50: 26 mg/kg; Oral-mouse LD50: 160 mg/kg

stimulation data    eye-rabbit 100 mg severe

explosive hazard characteristics    reaction with perchloric acid to generate sensitive explosive product

flammability hazard characteristics    when exposed to heat, the flame is flammable; Thermal decomposition of toxic chloride smoke

storage and transportation characteristics    The warehouse is ventilated and dried at low temperature; It is stored and transported separately from food raw materials and oxidants

 

Attribute	Details
Chemical Name	3-Chloro-1.2-propanediol
CAS Number	96-24-2
Synonyms	3-Chloro-1.2-dihydroxypropane; α-Chlorohydrin; 1-Chloro-2.3-propanediol; Glycerol-alpha-chlorohydrin
Molecular Formula	C3H7ClO2
Molecular Weight	110.54 g/mol
Chemical Structure	A propyl chain with a chlorine atom attached to the first carbon and hydroxyl groups attached to the second and third carbons
Appearance	Colorless to slightly yellow liquid
Melting Point	-40°C
Boiling Point	213°C (at 760 mmHg) or 139°C (at 2.39 kPa)
Density	1.322 g/cm³
Solubility	Soluble in water, methanol, ethanol, ether, acetone, and ethyl acetate; slightly soluble in toluene; insoluble in benzene, petroleum ether, and carbon tetrachloride
Refractive Index	1.479-1.481
Flash Point	135°C
Uses	Used as a solvent for cellulose acetate; in the manufacture of plasticizers, surfactants, dyes, pharmaceuticals, and glycerol derivatives; also used as an intermediate in organic synthesis
Safety Information	Highly toxic and suspected carcinogen; may cause irritation to eyes, skin, and respiratory system; may have adverse effects on the lungs, liver, kidneys, and brain; inhalation may cause nausea, headache, dizziness, and unconsciousness; may form explosive mixtures with air; store in a cool, dry place away from heat, sparks, and open flames; handle with caution and follow standard chemical safety procedures.

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