3-bromoiodobenzene

Semiconductor Display Materials 2025-03-04

 

Property 3-Bromoiodobenzene
Chemical Formula C₆H₄BrI
Molecular Weight 282.9 g/mol
Physical State Pale yellow liquid
Melting Point -9.3°C
Boiling Point 239.6°C at 760 mmHg
Density 2.215 g/cm³
Solubility Insoluble in water; soluble in chloroform, ethyl acetate

Preparation Methods

  • Halogenation Reactions: Synthesized by direct halogenation of benzene derivatives.
  • Metal-Catalyzed Coupling: Produced via transition metal-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi couplings).

Applications

  • Pharmaceutical Industry: Used as an intermediate in the synthesis of drug molecules.
  • Agrochemicals: Employed in the production of pesticides and fungicides.
  • Dyes and Pigments: Serves as a precursor for specialty dyes.
  • Electronic Materials: Utilized in the manufacture of semiconductors and conductive polymers.

Safety and Handling

  • Classification: Irritant (Xi); may cause skin and eye irritation.
  • Storage: Keep in a dark, cool place to avoid decomposition.
  • Handling: Use protective gloves, goggles, and a respirator.

Notes

  • Reactivity: The presence of both bromine and iodine makes it highly reactive in substitution and cross-coupling reactions.
  • Stability: Light-sensitive; prolonged exposure may lead to isomerization or decomposition.
  • Commercial Availability: Widely available from chemical suppliers in varying purities (e.g., 98% with copper stabilizer).

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