3-Bromo-5-methylphenol
Pharmaceutical Materials 2025-03-20
CAS.No：74204-00-5
Appearance: white powder
Molecular Formula :C7H7BrO
Molecular weight:187.03
Purity:≥99.5%
Capacity:20T/month
Application:Pharmaceutical intermediates
| Property | Details |
|---|---|
| Molecular Formula | C7H7BrO |
| Molecular Weight | 187.03 g/mol |
| CAS Number | 6940-78-9 |
| Appearance | White to off-white crystalline solid or powder |
| Purity | Typically ≥98% |
| Melting Point | 58-61 °C |
| Boiling Point | 240-242 °C (at 760 mmHg) |
| Density | 1.58 g/cm³ |
| Solubility | Soluble in organic solvents such as ethanol, ether, and DMSO; slightly soluble in water |
| Applications | Organic synthesis, pharmaceuticals, agrochemicals, and materials science |
| Safety Considerations | Handle with care; avoid contact with skin and eyes; store in a cool, dry place away from heat and open flames |
| Suppliers | Available from various chemical suppliers globally |
Applications
3-Bromo-5-methylphenol is a versatile compound widely used in organic synthesis, particularly in the production of brominated and methylated compounds. Its bromine and methyl substituents provide unique reactivity and physical properties, making it a valuable intermediate in the synthesis of various chemicals.
In pharmaceuticals, 3-Bromo-5-methylphenol is utilized in the development of drugs with enhanced biological activity and specificity. The bromine atom can be used in cross-coupling reactions to introduce diverse functional groups, while the methyl group can modulate the lipophilicity and metabolic stability of drug molecules.
In agrochemicals, this compound serves as a building block for the synthesis of herbicides and pesticides, offering improved potency and environmental safety. Additionally, 3-Bromo-5-methylphenol finds applications in materials science, where its brominated structure can be exploited to create polymers and materials with tailored properties.
Its solubility in organic solvents facilitates its use in various synthetic methodologies, while its stability under appropriate storage conditions ensures its reliability in research and industrial applications.
