
3-Amino-1,2-propanediol
3-Amino-1,2-propanediol (CAS No. 616-30-8)
1. Basic Information
IUPAC Name: 3-Amino-1,2-propanediol
Synonyms:
1-Aminoglycerol
3-Aminopropane-1,2-diol
CAS Number: 616-30-8
Molecular Formula: C...
Category:Agrochemicals
Introduction
3-Amino-1,2-propanediol (CAS No. 616-30-8)
1. Basic Information
- IUPAC Name: 3-Amino-1,2-propanediol
- Synonyms:
- 1-Aminoglycerol
- 3-Aminopropane-1,2-diol
- CAS Number: 616-30-8
- Molecular Formula: C₃H₉NO₂
- Molecular Weight: 91.11 g/mol
- Appearance: Colorless to pale yellow viscous liquid
- Odor: Mild amine-like odor
2. Physical and Chemical Properties
Property | Value |
---|---|
Melting Point | -20°C (-4°F) |
Boiling Point | 150–152°C (302–306°F) at 15 mmHg |
Density | 1.14 g/cm³ (20°C) |
Refractive Index | 1.465–1.475 (20°C) |
Solubility | – Water: Miscible |
– Organic solvents: Soluble in ethanol, methanol; insoluble in ether | |
Viscosity | ~200 cP (25°C) |
3. Chemical Structure
OH | HO-CH₂-CH-CH₂-NH₂
4. Hazards (GHS Classification)
- Health Hazards:
- Causes skin irritation (H315)
- Causes serious eye irritation (H319)
- Environmental: Not classified
- NFPA Rating: Health 2, Flammability 1, Reactivity 0
5. Storage and Handling
- Storage:
- Keep in tightly sealed containers under nitrogen
- Store in a cool, dry place (2–8°C recommended)
- Handling:
- Use nitrile gloves and safety goggles
- Work in a well-ventilated area
6. Applications
- Pharmaceuticals:
- Intermediate for β-blockers (e.g., labetalol)
- Chiral building block in drug synthesis
- Chemical Synthesis:
- Precursor for heterocycles (e.g., oxazolidinones)
- Biotechnology:
- Buffer component in biochemical assays