3-Amino-1,2-propanediol

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Category:Agrochemicals   Own Brand:MT  /MOQ:100KG  /From China/  B2B only.

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Introduction

3-Amino-1,2-propanediol (CAS No. 616-30-8) 


1. Basic Information

  • IUPAC Name: 3-Amino-1,2-propanediol
  • Synonyms:
    • 1-Aminoglycerol
    • 3-Aminopropane-1,2-diol
  • CAS Number: 616-30-8
  • Molecular Formula: C₃H₉NO₂
  • Molecular Weight: 91.11 g/mol
  • Appearance: Colorless to pale yellow viscous liquid
  • Odor: Mild amine-like odor

2. Physical and Chemical Properties

Property Value
Melting Point -20°C (-4°F)
Boiling Point 150–152°C (302–306°F) at 15 mmHg
Density 1.14 g/cm³ (20°C)
Refractive Index 1.465–1.475 (20°C)
Solubility – Water: Miscible
– Organic solvents: Soluble in ethanol, methanol; insoluble in ether
Viscosity ~200 cP (25°C)

3. Chemical Structure

   OH  
    |  
HO-CH₂-CH-CH₂-NH₂

4. Hazards (GHS Classification)

  • Health Hazards:
    • Causes skin irritation (H315)
    • Causes serious eye irritation (H319)
  • Environmental: Not classified
  • NFPA Rating: Health 2, Flammability 1, Reactivity 0

5. Storage and Handling

  • Storage:
    • Keep in tightly sealed containers under nitrogen
    • Store in a cool, dry place (2–8°C recommended)
  • Handling:
    • Use nitrile gloves and safety goggles
    • Work in a well-ventilated area

6. Applications

  • Pharmaceuticals:
    • Intermediate for β-blockers (e.g., labetalol)
    • Chiral building block in drug synthesis
  • Chemical Synthesis:
    • Precursor for heterocycles (e.g., oxazolidinones)
  • Biotechnology:
    • Buffer component in biochemical assays

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