Pharmaceutical Materials

Review of 3-(3-Hydroxyphenyl)propanoic Acid (CAS No.: 621-54-5)3-(3-Hydroxyphenyl)propanoic acid (CAS No.: 621-54-5), also known as m-hydroxyphenylpropionic acid, is a phenolic compound with significant biological activity and industrial applications. As a metabolite of flavonoids produced by human gut microbiota, it exhibits vasodilatory properties, making it relevant in cardiovascular research. Its synthesis routes often involve microbial transformations or chemical derivatization from precursors like 3-hydroxyphenylacetaldehyde. The compound is a white to light brown crystalline powder, soluble in water, ethanol, and ethyl ether, with a melting point of 111°C and a boiling point of 354.5°C at 760 mmHg. Pharmaceutically, it serves as an intermediate in drug synthesis and as a potential therapeutic agent for hypertension. Industrial applications include its use in specialty chemicals and as a building block for polymers.

Usage: Used as pharmaceutical intermediates.

Packaging and Shipping：25kg/drum or as per buyer’s requirements.

Storage: Storage in ventilated low temperature dry warehouse; Keep container closed and separately from open flame and heat source.

 

Name	3-(3-Hydroxyphenyl)propionic acid
Synonyms	IFLAB-BB F2119-0005 M-HYDROCOUMARIC ACID LABOTEST-BB LT00454600 3-Hydroxyhydrocinnamic acid 3-HYDROXYHYDROCINNAMIC ACID 3-(3-hydroxyl phenyl)propanol 3-hydroxy-benzenepropanoicaci 3-Hydroxyphenyl-propionic acid 3-(3-Hydroxyphenyl)propionic acid 3-(3-hydroxyphenyl)propanoic acid 3-(3-HYDROXYPHENYL)PROPIONIC ACID 3-(M-HYDROXYPHENYL)PROPIONIC ACID
CAS	621-54-5
EINECS	210-692-8
InChI	InChI=1/C9H10O3/c10-8-3-1-2-7(6-8)4-5-9(11)12/h1-3,6,10H,4-5H2,(H,11,12)

Molecular Formula	C9H10O3
Molar Mass	166.17
Density	1.260
Melting Point	111 °C
Boling Point	355℃
Flash Point	182℃
Solubility	Soluble in water, ethanol, ether
Vapor Presure	1.23E-05mmHg at 25°C
Appearance	White-like to white crystals.
Color	Pale Beige to Light Brown
BRN	1947445
pKa	4.68±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.58
MDL	MFCD00016554
Physical and Chemical Properties	Off-white to white crystals.

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