3-(2-Chloroacetyl)pyridine hydrochloride
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Category：Biomedicine Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
CAS.No：61889-48-3
Appearance:White powder
Molecular Formula:C7H7Cl2NO
Purity:HPLC≥99.5%
Molecular weight:0
Capacity:20 tons/month
Application:Pharmaceutical intermediates
Basic Information of 3-(2-Chloroacetyl)pyridine Hydrochloride
| Aspect | Details |
|---|---|
| Chemical Name | 3-(2-Chloroacetyl)pyridine Hydrochloride |
| CAS Number | 61889-48-3 |
| Molecular Formula | C₇H₇Cl₂NO |
| Molecular Weight | 192.04 g/mol |
| Appearance | White to yellow crystal powder |
| Melting Point | 245-250°C (decomp) |
| Solubility | Soluble in water and some organic solvents |
| Storage Conditions | Under inert gas (nitrogen or argon) at 2-8°C |
Additional Information on 3-(2-Chloroacetyl)pyridine Hydrochloride
| Aspect | Details |
|---|---|
| Synonyms | 2-Chloro-1-(3-pyridinyl)ethanone hydrochloride, Chloroacetylpyridine Hydrochloride, 2-Chloro-1-(pyridin-3-yl)ethan-1-one hydrochloride |
| Applications | – Pharmaceutical Synthesis: Used as a synthetic intermediate for the preparation of chiral amino(pyridinyl)ethanol.<br>- Enzymatic Kinetic Resolution: Utilized in the lipase-mediated kinetic resolution process to produce chiral compounds.<br>- Anticancer Drug Synthesis: Used in the synthesis of the anticancer drug cyclophosphamide. |
| Preparation Method | – Synthesized by reacting 2-chloroacetic acid with pyridine in an anhydrous environment, followed by reaction with hydrochloric acid to form the hydrochloride salt. |
| Safety Information | – Hazard Statements: H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), H335 (May cause respiratory irritation).<br>- Precautionary Statements: P264 (Wash hands thoroughly after handling), P270 (Do not eat, drink, or smoke when using), P280 (Wear protective gloves/protective clothing/eye protection/face protection), P301+P312 (IF SWALLOWED: Call a POISON CENTER/doctor/… if you feel unwell), P302+P352 (IF ON SKIN: Wash with plenty of water), P305+P351+P338 (IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing).<br>- Storage: Store in a cool, dry place under inert gas. |
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