Pharmaceutical Materials

2,6-Difluorobenzamide (CAS No. 18063-03-1) is a significant organic compound widely utilized in pharmaceuticals, agrochemicals, and materials science. Its molecular formula is C₇H₅F₂NO, with a molecular weight of 157.12 g/mol. This compound is recognized for its dual functionality, featuring fluorine and amide groups that enhance its reactivity and versatility in organic synthesis. As a crucial intermediate, it plays a pivotal role in the development of fluorinated benzoylurea insecticides, such as flufenoxuron and hexaflumuron, which are effective against a broad spectrum of pests. Additionally, its applications extend to medicinal chemistry, where it serves as a building block for drug discovery. The compound’s stability under normal conditions, coupled with its well-documented physical and chemical properties, makes it a reliable choice for industrial and research applications.

Usage： Used as pharmaceutical intermediate and Pesticide intermediate.

Packaging and Shipping： 25KG/drum.

Storage: Keep container sealed and store in an ventilated, low temperature, dry warehouse, separate from foods and oxidizing agents.

Name	2,6-Difluorobenzamide
Synonyms	uorobenzamide 2,6-Difluorbenzamid 2,6-Difluorobenzamide 2,6-Difluorobenzoylamide Fluorine benzaMide 2, 6-2 2,6-difluorobenzoic acid amide
CAS	18063-03-1
EINECS	241-972-8
InChI	InChI=1/C7H5F2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)
InChIKey	AVRQBXVUUXHRMY-UHFFFAOYSA-N

Molecular Formula	C7H5F2NO
Molar Mass	157.12
Density	1,199g/cm
Melting Point	145-148 °C (lit.)
Boling Point	51-52C/15Tor
Flash Point	67.3°C
Solubility	ethanol: soluble5%, clear to turbid, colorless to light yellow
Vapor Presure	0.622mmHg at 25°C
Appearance	White crystal
Color	Off-White
BRN	2047480
pKa	14.54±0.50(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1,508
MDL	MFCD00007972
Physical and Chemical Properties	Appearance: White-like crystals
Use	It can be used as an intermediate for the synthesis of fluorinated benzoylurea pesticides, and can be used as a variety of insecticides and acaricides, such as fluifolide, difenuron, and difenuron. It is also used in medicine; Intermediates in pesticides and intermediates in organic synthesis for the synthesis of fluorobenzenes Acyl urea pesticide intermediates, from which can be prepared by the fluoride, borteuron, difenuron and other insecticidal, acaricide. It is also used in medicine, liquid crystal materials.

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