2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate
Category：Pharmaceutical Materials
Introduction
2,6-diazaspiro [3,3] heptane-2-carboxylic acid tert butyl ester hemioxalate is a compound commonly referred to as TFA.
nature:
-TFA is a colorless to light yellow liquid with a pungent odor.
-It has good solubility and is soluble in various organic solvents.
-It is a strong acid that can react with bases to form corresponding salts.
-TFA can decompose and produce toxic gases at high temperatures.
Purpose:
-TFA is often used as an acidic catalyst in organic synthesis.
-It is also widely used as a substitute for hydrofluoric acid in protein analysis and synthesis.
-TFA can also be used as a solvent, cleaning agent, and strong acid conversion agent for polymers.
Manufacturing method:
-The preparation of TFA is mainly achieved by reacting trifluoroacetic acid with the corresponding alcohol ester.
Security information:
-TFA is corrosive and irritating, and skin and eye contact should be avoided.
-When using TFA, chemical protective gloves, goggles, and protective clothing should be worn.
-Avoid contact with strong bases and oxidants to prevent dangerous chemical reactions.
-The gas produced by the decomposition of TFA is harmful to human health and should be operated in a well ventilated environment.
| Name | 2-Methyl-2-propanyl 2,6-diazaspiro[3.3]heptane-2-carboxylate ethanedioate (2:1) |
| Synonyms | 2,6-Diazaspiro[3.3]heptane, N2-BOC protected hemioxalate tert-butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate tert-Butyl 2,6-diazaspiro[3,3]heptane-2-carboxylate hemioxalate tert-Butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate, hemioxalate salt 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester heMioxylate 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid 1,1-dimethylethyl ester ethanedioate 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 1,1-diMethylethyl ester, heMioxalate 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid ethanedioate, 1,1-dimethylethyl ester |
| CAS | 1041026-71-4 |
| InChI | InChI=1S/2C10H18N2O2.C2H2O4/c2*1-9(2,3)14-8(13)12-6-10(7-12)4-11-5-10;3-1(4)2(5)6/h2*11H,4-7H2,1-3H3;(H,3,4)(H,5,6) |
| Molecular Formula | C22H38N4O8 |
| Molar Mass | 486.56 |
| Melting Point | 206-209℃ |
| Water Solubility | Slightly soluble in water. |
| Solubility | DMSO (Slightly, Heated), Methanol (Slightly, Sonicated) |
| Appearance | Solid |
| Color | White to Off-White |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Stability | Hygroscopic |
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