Pharmaceutical Materials

2,6-diazaspiro [3,3] heptane-2-carboxylic acid tert butyl ester hemioxalate is a compound commonly referred to as TFA.

nature:

-TFA is a colorless to light yellow liquid with a pungent odor.

-It has good solubility and is soluble in various organic solvents.

-It is a strong acid that can react with bases to form corresponding salts.

-TFA can decompose and produce toxic gases at high temperatures.

Purpose:

-TFA is often used as an acidic catalyst in organic synthesis.

-It is also widely used as a substitute for hydrofluoric acid in protein analysis and synthesis.

-TFA can also be used as a solvent, cleaning agent, and strong acid conversion agent for polymers.

Manufacturing method:

-The preparation of TFA is mainly achieved by reacting trifluoroacetic acid with the corresponding alcohol ester.

Security information:

-TFA is corrosive and irritating, and skin and eye contact should be avoided.

-When using TFA, chemical protective gloves, goggles, and protective clothing should be worn.

-Avoid contact with strong bases and oxidants to prevent dangerous chemical reactions.

-The gas produced by the decomposition of TFA is harmful to human health and should be operated in a well ventilated environment.

Name	2-Methyl-2-propanyl 2,6-diazaspiro[3.3]heptane-2-carboxylate ethanedioate (2:1)
Synonyms	2,6-Diazaspiro[3.3]heptane, N2-BOC protected hemioxalate tert-butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate tert-Butyl 2,6-diazaspiro[3,3]heptane-2-carboxylate hemioxalate tert-Butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate, hemioxalate salt 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester heMioxylate 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid 1,1-dimethylethyl ester ethanedioate 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 1,1-diMethylethyl ester, heMioxalate 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid ethanedioate, 1,1-dimethylethyl ester
CAS	1041026-71-4
InChI	InChI=1S/2C10H18N2O2.C2H2O4/c2*1-9(2,3)14-8(13)12-6-10(7-12)4-11-5-10;3-1(4)2(5)6/h2*11H,4-7H2,1-3H3;(H,3,4)(H,5,6)

Molecular Formula	C22H38N4O8
Molar Mass	486.56
Melting Point	206-209℃
Water Solubility	Slightly soluble in water.
Solubility	DMSO (Slightly, Heated), Methanol (Slightly, Sonicated)
Appearance	Solid
Color	White to Off-White
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Stability	Hygroscopic

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