2′,4′-Dichloroacetophenone CAS: 2234-16-4
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Category：Chemical Intermediates MOQ:100KG Shipped directly from China
Introduction
CAS: 2234-16-4
Appearance: White to off-white crystals
Purity: ≥99% Capacity: 2000mt/year MOQ: 100g
Application: Pharmaceutical/pesticide intermediate
Standard: Enterprise export
Manufacturer: Jinan Finer Chemical Co., Ltd
Synonyms: 1-(2,4-Dichlorophenyl)ethanone
Molecular Formula: C8H6Cl2O
Molecular Weight: 189.04
CAS Registry Number: 2234-16-4
EINECS: 218-780-8
Density: 1.32
Melting point: 29-34 ºC
Boiling point: 242 ºC
Refractive index: 1.5635
Flash point: 131 ºC
Water solubility: ca. 200 mg/L
2′,4′-Dichloroacetophenone, with the CAS number 2234-16-4, is an organic compound characterized by its white to grayish crystalline appearance. This compound serves as an important intermediate in the pharmaceutical industry, particularly for the synthesis of ketoconazole and other antifungal agents. It exhibits specific physicochemical properties that make it suitable for various chemical reactions and formulations. Due to its halogenated aromatic structure, 2′,4′-Dichloroacetophenone demonstrates stability and reactivity, enabling its use in a range of synthetic pathways.
| Property Category | Details |
|---|---|
| Chemical Name | 2′,4′-Dichloroacetophenone |
| CAS Number | 2234-16-4 |
| Molecular Formula | C8H6Cl2O |
| Molecular Weight | 189.04 g/mol |
| Physical Properties | |
| – Appearance | White to grayish crystals |
| – Density | 1.3 ± 0.1 g/cm³ |
| – Melting Point | 33-34 °C |
| – Boiling Point | 246.7 ± 20.0 °C at 760 mmHg |
| – Refractive Index | 1.549-1.5635 |
| – Flash Point | 100.9 ± 22.3 °C |
| Chemical Properties | |
| – Solubility in Water | ca. 200 mg/L |
| – Vapor Pressure | 0.0268 mmHg at 25 °C |
| – LogP | 2.79 |
| – Stability | Stable, avoid contact with oxides |
| – Uses | Pharmaceutical intermediate, synthesis of ketoconazole |
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