2,4-Dichloro-5-methoxypyrimidine CAS No.19646-07-2
CAS No.19646-07-2
Attribute
Details
Chemical Name
2.4-Dichloro-5-methoxypyrimidine
CAS Number
19646-07-2
Synonyms
5-Methoxy-2.4-dichloropyrimidine; 2.4-Dichloro-5-methoxy-1.3-diaz...
Category：Pharmaceutical Materials
Introduction
CAS No.19646-07-2
| Attribute | Details |
|---|---|
| Chemical Name | 2.4-Dichloro-5-methoxypyrimidine |
| CAS Number | 19646-07-2 |
| Synonyms | 5-Methoxy-2.4-dichloropyrimidine; 2.4-Dichloro-5-methoxy-1.3-diazine; Pyrimidine, 2.4-dichloro-5-methoxy- |
| Molecular Formula | C5H4Cl2N2O |
| Molecular Weight | 179.00 g/mol |
| Appearance | White or pale yellow solid |
| Melting Point | 68°C |
| Boiling Point | 259.9°C at 760 mmHg |
| Flash Point | 111°C |
| Density | 1.446 g/cm³ |
| Refractive Index | 1.541 |
| Solubility | Good solubility in polar solvents, poor solubility in water |
| Usage | Used as an intermediate in organic synthesis, particularly in the synthesis of heterocyclic compounds. It is also a key intermediate in the pharmaceutical industry for the production of certain drugs. |
| Reactivity | The chlorine atoms at the 2- and 4-positions can undergo substitution reactions, with the 4-position chlorine atom being more reactive. |
| Synthesis Method | Typically synthesized by reacting 5-methoxyuracil with pyridine and phosphorus oxychloride under high temperature and pressure. |
| Safety Information | Handle with care. May be irritating to skin and eyes. Store in a cool, dry place, away from heat and flame. Refer to the Material Safety Data Sheet (MSDS) for detailed safety precautions and disposal methods. |
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