Pharmaceutical Materials

CAS Number: 695-98-7

Molecular Formula: C8H11N

Molecular Weight: 121.18 g/mol

Appearance: Colorless or pale yellow liquid

Boiling Point: 185°C

Usage: Used as a pharmaceutical intermediate and a good solvent.

 

Aspect	Details
Name	2.3.5-Collidine
Common Synonyms	2.3.5-Trimethylpyridine; 2.3.5-Lutidine
CAS No.	108-75-8
Molecular Formula	C₈H₁₁N
Molecular Weight	121.18 g/mol
Physical Properties	Appearance: Colorless to pale yellow liquid Boiling Point: 189-191 °C Melting Point: -13 °C Solubility: Soluble in organic solvents (e.g., ethanol, ether); slightly soluble in water Density: 0.93 g/cm³
Chemical Properties	A tertiary amine with a pyridine ring substituted with three methyl groups at positions 2. 3. and 5. It is a stronger base than pyridine due to the electron-donating effects of the methyl groups, enhancing its nucleophilicity and reactivity in substitution reactions.
Applications	Used as a solvent and catalyst in organic synthesis Employed in pharmaceuticals for the preparation of nucleoside analogs Acts as a ligand in coordination chemistry and as a base in acid-base titrations
Safety Information	Handle with caution due to its irritant properties; avoid inhalation and prolonged skin contact Store in a cool, dry place away from strong acids and oxidizing agents

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