2,2,6,6-Tetramethylpiperidinooxy CAS No. 2564-83-2
Pharmaceutical Materials 2025-03-20
2.2.6.6-Tetramethylpiperidinooxy is widely used in chemistry, biology, food industry, agriculture and other fields. It has the functions of capturing free radicals, quenching singlet oxygen and selective oxidation.
Product Name
2.2.6.6-Tetramethylpiperidinooxy
Multiple Names
2.2.6.6-Tetramethylpiperidinooxy;
TEMPO;
2.2.6.6-Tetramethyl-1-Piperidinyloxy, Free Radical;
2.2.6.6-Tetramethyl-1-Piperinedinyloxy;
2.2.6.6-Tetramethylpiperidin-1-Ol;
(2.2.6.6-Tetramethylpiperidin-1-Yl)Oxidanyl;
2.2.6.6-Tetramethylpiperidine 1-Oxyl;
2.2.6.6-Tetramethyl-1-Piperidinyloxy
CAS No. 2564-83-2; 125012-91-1; 126517-51-9; 25657-03-8; 26933-82-4; 54637-06-8; 64104-42-3
EC No. 219-888-8
MF No. C9H18NO
MW No. 156.2453
Advantage of 2.2.6.6-Tetramethylpiperidinooxy CAS No. 2564-83-2
Good water solubility and stability
The reaction conditions are mild
High yield, good selectivity, good stability, recyclable
| Aspect | Details |
|---|---|
| Chemical Name | 2.2.6.6-Tetramethylpiperidinooxy |
| Other Names | Tempo, 4-Oxo-2.2.6.6-tetramethylpiperidine-1-oxyl |
| CAS Number | 2564-83-2 |
| Molecular Formula | C₉H₁₇NO |
| Molecular Weight | 155.24 g/mol |
| Physical State | Orange-red crystalline solid |
| Melting Point | 41 – 43°C (106 – 109°F) |
| Boiling Point | Sublimes at around 100°C (212°F) under reduced pressure |
| Density | 0.91 g/cm³ at 20°C |
| Solubility | Soluble in water, ethanol, and acetone. Less soluble in non-polar solvents like hexane and benzene. |
| Synthesis Method | Commonly prepared by the oxidation of 2.2.6.6-tetramethylpiperidine with an oxidizing agent such as potassium peroxodisulfate in an aqueous solution. |
| Applications | A well-known stable nitroxide radical used as a selective and efficient organic catalyst in various oxidation reactions, including alcohol oxidation and olefin epoxidation. Also employed as a spin probe in electron spin resonance (ESR) spectroscopy for studying polymer dynamics and biochemistry. |
| Safety Precautions | May cause irritation to the eyes, skin, and respiratory system. Handle with appropriate protective equipment and in a well-ventilated area. |
