2,2-Dimethylbutyryl chloride

We are a manufacturer based in China, specializing in high-quality 2,2-Dimethylbutyryl chloride for industrial clients worldwide. Technical support and custom formulation available.

Category：Pharmaceutical Materials  |  Brand：MT

Factory Direct 7-30 Days Lead Time MOQ: 100KG Global Export

Introduction

CAS Number: 5856-77-9

Molecular Formula: C6H11ClO

Molecular Weight: 134.60 g/mol

Appearance: Transparent to pale yellow liquid

Boiling Point: 133°C

Flash Point: 29°C

Usage: Used as a chemical intermediate.

 

Aspect Details
Name 2.2-Dimethylbutyryl Chloride
Common Synonyms Neopentanoyl Chloride, Pivaloyl Chloride (alternate naming in some contexts), 2.2-Dimethylbutanoyl Chloride
CAS No. 3282-30-2
Molecular Formula C₆H₁₁ClO
Molecular Weight 134.60 g/mol
Physical Properties
  • Appearance: Colorless to pale yellow liquid
  • Boiling Point: 142-144 °C (at 760 mmHg)
  • Density: 0.988 g/cm³ (approximate)
  • Solubility: Reacts with water; soluble in organic solvents like chloroform, ether
Chemical Properties
  • Highly reactive acyl chloride derivative
  • Sensitive to moisture; hydrolyzes rapidly in water
  • Participates in Friedel-Crafts acylation and amide/ester formation reactions
Applications
  • Used as a reagent in pharmaceutical synthesis (e.g., preparation of amide drugs)
  • Employed in agrochemical production for pesticide intermediates
  • Utilized in specialty chemical synthesis for fragrances and polymers
Safety Information
  • Corrosive (C); irritant (Xi)
  • Wear PPE (gloves, goggles) to avoid skin/eye contact
  • Store in a dry, well-ventilated area, away from alcohols and amines

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