2(1H)-Pyridinone,3-chloro-4-hydroxy-(9CI)
Category：Active Pharmaceutical Ingredients
Introduction
2(1H)-Pyridinone,3-chloro-4-hydroxy-(9CI) – Names and Identifiers
| Name | 2(1H)-Pyridinone,3-chloro-4-hydroxy-(9CI) |
| Synonyms | 3-Chloro-2,4-dihydroxypyridine 5-Chloro-4-hydroxy pyridinone-2 3-Chloro-4-hydroxy-2(1H)-pyridinone 3-chloro-2-hydroxypyridin-4(1H)-one 3-chloro-2-hydroxy-1H-pyridin-4-one 3-Chloro-4-hydroxypyridin-2(1H)-one 2(1H)-Pyridinone, 3-chloro-4-hydroxy- 2(1H)-Pyridinone,3-chloro-4-hydroxy-(9CI) 3-chloro-4-hydroxy-1,2-dihydropyridin-2-one |
| CAS | 103792-81-0 |
| InChI | InChI=1/C5H4ClNO2/c6-4-3(8)1-2-7-5(4)9/h1-2H,(H2,7,8,9) |
2(1H)-Pyridinone,3-chloro-4-hydroxy-(9CI) – Physico-chemical Properties
| Molecular Formula | C5H4ClNO2 |
| Molar Mass | 145.54 |
| Density | 1.56 |
| Melting Point | 310 °C (decomp) |
| Boling Point | 283 ºC |
| Flash Point | 125 ºC |
| Vapor Presure | 0.00412mmHg at 25°C |
| pKa | 4.50±1.00(Predicted) |
| Storage Condition | Room Temprature |
| Refractive Index | 1.617 |
| MDL | MFCD11101041 |
2(1H)-Pyridinone,3-chloro-4-hydroxy-(9CI) – Introduction
3-Chloro-2, 4-dihydroxypyridine is an organic compound with the chemical formula C5H4ClNO2, often abbreviated as 3-Cl-2,4-DHP. The following is an introduction to some of its properties, uses, methods and safety information:
Nature:
1. Appearance: 3-chloro-2, 4-dihydroxypyridine is a colorless to pale yellow crystalline solid.
2. Melting point: Its melting point is about 228-230 degrees Celsius.
3. Solubility: 3-chlorine -2, 4-dihydroxypyridine has low solubility in water, but it can be dissolved in organic solvents such as alcohol, ether, etc.
Use:
1. Pesticide: 3-Chloro-2, 4-dihydroxypyridine is a broad-spectrum pesticide that can be used to control pests on a variety of agricultural crops.
2. Medicine: It is also used as a pharmaceutical intermediate and can be used to synthesize other compounds with medicinal value.
Preparation Method:
3-Chloro-2, 4-dihydroxypyridine is mainly prepared by the following methods:
1. Hydroxylation method: it is obtained by reacting 2,4-dihydroxypyridine with cuprous chloride, and then further hydroxylation with silver chloride.
2. Hydroxychlorination method: it is obtained by reacting 2,4-dihydroxypyridine with cuprous chloride under the catalysis of stannous chloride.
3. hydroxylation-chlorination method: by reacting 2,4-dihydroxypyridine with sodium chlorite to obtain an intermediate product, and then reacting with chlorous acid and sodium chloride for hydroxylation.
Safety Information:
The following points should be noted when using 3-chloro-2, 4-dihydroxypyridine:
1. Avoid direct contact: gloves and protective glasses should be used when handling 3-chloro-2, 4-dihydroxypyridine to avoid skin and eye irritation or damage.
2. storage note: 3-chlorine -2, 4-dihydroxypyridine should be stored in a dry, cool place, away from fire and oxidant, avoid high temperature and direct sunlight.
3. Toxic effects: 3-chloro-2, 4-dihydroxypyridine has certain toxicity, and long-term exposure or exposure may cause health effects. Relevant safety data should be read carefully before use and chemical safety procedures should be strictly followed.,Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.
