2-Thiopheneacetic acid
Pharmaceutical Materials 2025-03-02
CAS Number: 1918-77-0
Molecular Formula: C6H6O2S
Molecular Weight: 142.18 g/mol
Appearance: White or slightly yellow crystalline powder Melting Point: 61-67°C
Usage: It is used as an intermediate in the production of cephalosporins and other pharmaceuticals.
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| Attribute | Details |
|---|---|
| Chemical Name | 2-Thiopheneacetic acid |
| Synonyms | 2-(Thiophen-2-yl)acetic acid; Thiophene-2-acetic acid; 2-Thiophenacetic acid; 2-(2-Thienyl)acetic acid; α-Thiophenylacetic acid; 2-Thiophen-2-ylacetic acid; 2-Thiophene-acetic acid; 2-Thiophenylacetic acid; 2-Thiophene acetic acid; 2-Thiophene-2-acetic acid |
| CAS Number | 532-27-4 |
| EINECS Number | 208-537-7 |
| Molecular Formula | C6H6O2S |
| Molecular Weight | 142.17 g/mol |
| Appearance | White to off-white crystalline powder |
| Melting Point | 120-123 °C (lit.) |
| Boiling Point | 270.3±23.0 °C (predicted) |
| Density | 1.323 g/cm³ (at 20 °C) |
| Solubility | Soluble in water, ethanol, ether, and acetone |
| pH | Acidic (forms carboxylic acid salts in aqueous solutions) |
| Stability | Stable under normal conditions; incompatible with oxidizing agents and bases |
| Uses | Intermediate in the synthesis of pharmaceuticals, pesticides, and dyes Used as a starting material for the preparation of heterocyclic compounds and other organic chemicals |
| Production Method | Typically synthesized through the condensation of thiophene with chloroacetic acid or its esters, followed by hydrolysis |
