2-Thiobarbituric Acid CAS No. 504-17-6
Pharmaceutical Materials 2025-03-20
It is used as electroplating additive, biochemical reagent, rhodium analysis reagent and pharmaceutical intermediate.
Product Name
2-Thiobarbituric Acid
Multiple Names
4.6-Dihydroxy-2-Mercaptopyrimidine;
2-Mercapto-4.6-Dihydroxypyrimidine;
6-Hydroxy-2-Thioxo-2.3-Dihydropyrimidin-4(1H)-One;
2-Thioxodihydropyrimidine-4.6(1H,5H)-Dione;
2-Mercapto-4.6-Dihydrocypyrimidine
CAS No. 504-17-6
EC No. 207-985-8
MF No. C4H4N2O2S
MW No. 144.1518
Advantage of 2-Thiobarbituric Acid CAS No. 504-17-6
It is an important pharmaceutical intermediate for the synthesis of purines and purine derivatives
Easy storage and stable performance.
It is widely used in medicine and pesticide intermediate industry.
| Aspect | Details |
|---|---|
| Chemical Name | 2-Thiobarbituric Acid |
| Aliases | 4.6-Dihydroxy-2-mercaptopyrimidine; TBA |
| CAS Number | 504-17-6 |
| Molecular Formula | C₄H₄N₂O₂S |
| Molecular Weight | 144.15 g/mol |
| Physical State | White to off-white crystalline powder |
| Melting Point | 235°C (decomposes) |
| Solubility | Soluble in hot water, alcohol, ether, alkalis, and sodium carbonate solutions; slightly soluble in cold water |
| Chemical Properties | Contains a thiobarbiturate structure with a mercapto group and two hydroxyl groups on a pyrimidine ring. It can react with aldehydes to form colored complexes, particularly useful in biochemical assays. |
| Applications | – Biochemical Assays: Widely used in the TBA method to measure malondialdehyde (MDA), a marker of lipid peroxidation, in biological samples. – Analytical Reagent: Acts as a reagent in qualitative and quantitative analysis of various compounds. – Electroplating Additive: Utilized in electroplating processes to improve the quality of metal coatings. |
| Safety Precautions | Irritant to eyes, respiratory system, and skin. Proper protective equipment, such as gloves and goggles, should be worn during handling. |
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