2-Quinoxalinone
2-Quinoxalinone
Chemical Name: 2(1H)-Quinoxalinone
Synonyms: Quinoxalin-2-one; 1,4-Dihydro-2-quinoxalinone
CAS Number: 1196-57-2
Molecular Formula: C₈H₆N₂O
Molecular Weight: 146.15 g/mol
Physical ...
Category：Agrochemicals
Introduction
2-Quinoxalinone
Chemical Name: 2(1H)-Quinoxalinone
Synonyms: Quinoxalin-2-one; 1,4-Dihydro-2-quinoxalinone
CAS Number: 1196-57-2
Molecular Formula: C₈H₆N₂O
Molecular Weight: 146.15 g/mol
Physical & Chemical Properties
| Property | Specification |
|---|---|
| Appearance | Off-white to pale yellow crystalline powder |
| Melting Point | 270-272°C (dec.) |
| Solubility | Slightly soluble in water; soluble in DMSO, DMF |
| UV λmax | 230, 300 nm (methanol) |
| pKa | ~8.5 (lactam NH) |
Hazard & Safety Information (GHS)
Warning Symbols:
⚠️ Acute Toxicity (Category 4)
⚠️ Skin/Eye Irritant (Category 2)
Hazard Codes:
• H302: Harmful if swallowed
• H315: Causes skin irritation
• H319: Causes serious eye irritation
Precautionary Measures:
• P264: Wash hands after handling
• P280: Wear gloves/eye protection
• P305+P351+P338: Eye rinse procedure
Chemical Behavior
• Tautomerism: Exists in keto-enol equilibrium
• Reactivity:
- Forms N-alkylated derivatives with alkyl halides
- Coordinates with metals via N,O-chelation
• Stability: Stable under normal conditions
Applications
✔ Pharmaceutical Intermediate:
- Antibacterial/antiviral agents
- Kinase inhibitors
✔ Coordination Chemistry: - Ligand for transition metals
✔ Material Science: - Fluorescent probes
Factory & Shipment
