2-Pyridinol-1-oxide
Pharmaceutical Materials 2025-03-02
CAS Number: 13161-30-3
Molecular Formula: C5H5NO2
Molecular Weight: 111.099 g/mol
Appearance: Greyish-white to light yellow solid powder
Usage: Applied in the preparation of metal-organic complexes and as an intermediate in organic synthesis.
Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.
| Property | Details |
|---|---|
| Molecular Formula | C5H5NO2 |
| Molecular Weight | 111.10 g/mol |
| CAS Number | 1328-53-6 |
| Appearance | White to off-white crystalline solid or powder |
| Purity | Typically ≥98% |
| Melting Point | 128-130 °C |
| Boiling Point | Decomposes before boiling |
| Density | ~1.2 g/cm³ (predicted) |
| Solubility | Soluble in water, ethanol, and DMSO; slightly soluble in ether |
| Applications | Organic synthesis, pharmaceuticals, and chemical intermediates |
| Safety Considerations | Handle with care; avoid contact with skin and eyes; store in a cool, dry place away from moisture and strong acids |
| Suppliers | Available from various chemical suppliers globally |
Applications
2-Pyridinol-1-oxide is a versatile compound used in organic synthesis, pharmaceuticals, and as a chemical intermediate. Its unique structure, featuring a pyridine ring with a hydroxyl group and an oxide function, provides distinct reactivity and physical properties, making it a valuable component in the synthesis of various chemicals.
In organic synthesis, 2-Pyridinol-1-oxide serves as a building block for the synthesis of complex molecules, such as pyridine derivatives and heterocyclic compounds. Its hydroxyl group can be functionalized to introduce diverse chemical groups, allowing for the creation of new molecules with tailored properties.
In pharmaceuticals, this compound is utilized in the development of drugs with diverse biological activities. The oxide function can be reduced or modified to enhance the pharmacological activity of drug molecules, contributing to improved therapeutic outcomes.
As a chemical intermediate, 2-Pyridinol-1-oxide is employed in the synthesis of various organic compounds, including dyes, pesticides, and ligands for coordination chemistry. Its solubility in water and organic solvents facilitates its use in various synthetic methodologies, while its stability under appropriate storage conditions ensures its reliability in research and industrial applications.
