2-Mercaptoethanol

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Category:Food Additives   Own Brand:MT  /MOQ:100KG  /From China/  B2B only.

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Introduction

 

Attribute Details
Chemical Name 2-Mercaptoethanol
Synonyms β-Mercaptoethanol, 2-Hydroxyethyl Mercaptan, Thioglycol
CAS Number 60-24-2
Formula C2H6OS
Molecular Weight 78.13 g/mol
Appearance Colorless volatile liquid with a strong odor
Physical Properties Density: 1.115 g/cm³; Melting Point: -100°C; Boiling Point: 157°C; Flash Point: 73.9°C
Solubility Soluble in water, alcohols, and ethers; insoluble in hydrocarbons
Chemical Role Reducing agent in organic reactions
Biological Applications – Reducing disulfide bonds in proteins and nucleic acids, altering their conformation and function
– Commonly used in SDS-PAGE sample buffers at a concentration of 5%
– Protects free cysteine thiol groups in proteins from forming disulfide bonds
Safety Precautions Irritant to eyes and skin; toxic if inhaled, ingested, or absorbed through skin
Wear appropriate protective equipment and handle in a well-ventilated area

2-Mercaptoethanol, also known as β-Mercaptoethanol or Thioglycol, is a colorless volatile liquid with a strong odor. It has a CAS number of 60-24-2 and a molecular weight of 78.13 g/mol. This compound is soluble in water, alcohols, and ethers but insoluble in hydrocarbons.

In organic reactions, 2-Mercaptoethanol serves as a reducing agent. In biological applications, it is commonly used to reduce disulfide bonds in proteins and nucleic acids, altering their conformation and function. It is also employed in SDS-PAGE sample buffers at a concentration of 5% and can protect free cysteine thiol groups in proteins from forming disulfide bonds.

However, 2-Mercaptoethanol is an irritant to eyes and skin and is toxic if inhaled, ingested, or absorbed through skin. Therefore, appropriate protective equipment should be worn, and it should be handled in a well-ventilated area.

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