2-Deoxy-D-ribose CAS No.:100-74-3
Biochemical Materials 2025-03-18
2-Deoxy-D-ribose
CAS No.: 533-67-5
Molecular Formula: C₅H₁₀O₄
Molecular Weight: 134.13 g/mol
1. Basic Properties
| Parameter | Specification |
|---|---|
| Appearance | White to off-white powder |
| Purity | ≥99.0% (HPLC) |
| Melting Point | 89-90°C (lit.) |
| Boiling Point | 167°C (est.) |
| Density | ~1.06 g/cm³ (est.) |
| Solubility | Water-soluble |
2. Key Applications
- Antiviral Drug Synthesis:
- Core intermediate for zidovudine (AZT), lamivudine, stavudine
- Used in HIV/hepatitis B therapeutics
- Oncology:
- Building block for antitumor nucleoside analogs
- Biochemical Research:
- Substrate for DNA/RNA studies
3. Storage & Handling
| Condition | Requirement |
|---|---|
| Packaging | 25 kg/cardboard drum |
| Temperature | ≤25°C |
| Humidity | ≤60% RH |
| Light Sensitivity | Light-sensitive (amber containers recommended) |
4. Safety Information
| Aspect | Details |
|---|---|
| GHS Classification | Not classified as hazardous |
| Stability | Hygroscopic; store under inert gas for long-term preservation |
5. Regulatory & Quality
- Pharmaceutical Grade: Complies with USP/EP standards
- Customization: Available in GMP-grade (≥99.5%)
- Shelf Life: 36 months when stored properly
Synonyms:
D-2-Deoxyribose | 2-Deoxy-D-erythro-pentose
