Pharmaceutical Materials

2-Cyanopyridine

Pharmaceutical Materials 2025-03-02

CAS Number: 100-70-9

Molecular Formula: C6H4N2

Molecular Weight: 104.11 g/mol

Appearance: White to pale yellow crystals at low temperatures

Solubility: Insoluble in water

Usage: Mainly used as an intermediate in pharmaceuticals, pesticides, and organic synthesis.

Aspect	Details
Name	2-Cyanopyridine
Common Synonyms	2-Pyridinecarbonitrile, Picolinonitrile, α-Cyanopyridine
CAS No.	100-70-9
Molecular Formula	C₆H₄N₂
Molecular Weight	104.11 g/mol
Physical Properties	Appearance: White to light yellow crystalline solid or liquid at elevated temperatures Melting Point: 26-28 °C Boiling Point: 212-215 °C Solubility: Insoluble in water; soluble in polar organic solvents like DMSO, ethanol Density: 1.081 g/cm³
Chemical Properties	Features a pyridine ring substituted with a cyano (-CN) group at the 2-position Acts as a weak base due to the pyridine nitrogen Reacts with nucleophiles (e.g., amines, alcohols) at the cyano group
Applications	Used as an intermediate in pharmaceuticals (e.g., antivirals, antibiotics) and agrochemicals Employed in organic synthesis for constructing heterocyclic compounds Utilized in dye and pigment production
Safety Information	Flammable; avoid open flames and heat sources Toxic by ingestion; handle with gloves and eye protection Store in a cool, dry place, away from oxidizing agents

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2-Cyanopyridine

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