Pharmaceutical Materials

2-Chlorotrityl chloride (CAS No.: 42074-68-0) is a crucial organic compound widely utilized in organic synthesis and pharmaceutical chemistry. It serves as a vital intermediate in the production of various pharmaceuticals, including the antifungal agent clotrimazole. This compound is characterized by its molecular formula C19H14Cl2 and a molecular weight of 313.22 g/mol. Under normal conditions, it appears as a grayish-white to yellow crystalline solid. Due to its structure featuring three benzene rings and two chlorine atoms, it exhibits good chemical stability and resistance to decomposition under standard conditions. The chlorine atom on the tertiary alkyl carbon is highly reactive and readily undergoes substitution reactions, making it an effective leaving group in nucleophilic substitution reactions. These properties make 2-chlorotrityl chloride an essential reagent in the synthesis of complex organic molecules and pharmaceuticals.

Usage： Intermediate of Clotrimazole.

Packaging and Shipping： 25KG/drum.

Storage: Stored in a dry and ventilated warehouse; keep away from sunshine; avoid fire; avoid moisture.

Name	2-Chlorotritylchloride polymer resin
Synonyms	KNORR-TRT(2-CL)-RESIN o-Chloro-tritylchloride 2-Chlorotrityl chloride ClotriMazole IMpurity C KNORR-2-CHLOROTRITYL RESIN o-ChlorotriphenylchloroMethane 2-Chlorotritylchloride polymer resin Diphenyl-2-chlorophenylMethyl Chloride 1-Chloro-2-(chlorodiphenylmethyl)Benzene (chloro(2-chlorophenyl)Methylene)dibenzene Chloro(2-chlorophenyl)diphenylmethane(2-Chlorophenyl)diphenylmethyl Chloride
CAS	42074-68-0
EINECS	255-647-3
InChI	InChI=1/C19H14Cl2/c20-18-14-8-7-13-17(18)19(21,15-9-3-1-4-10-15)16-11-5-2-6-12-16/h1-14H

Molecular Formula	C19H14Cl2
Molar Mass	313.22
Density	1.222±0.06 g/cm3(Predicted)
Melting Point	130-135°C
Boling Point	421.3±40.0 °C(Predicted)
Flash Point	194.2°C
Solubility	Soluble in Chloroform, methanol and dichloromethane, insoluble in water
Vapor Presure	6.44E-07mmHg at 25°C
Appearance	Powder
Color	Pale yellow crystalline powder
BRN	1983914
Storage Condition	2-8°C
Refractive Index	1.614
MDL	MFCD00040399
Physical and Chemical Properties	Crystallization. Melting point 130-134 °c.

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