2-Chlorothiophene

We are a manufacturer based in China, specializing in high-quality 2-Chlorothiophene for industrial clients worldwide. Technical support and custom formulation available.

Category：Pharmaceutical Materials  |  Brand：MT

Factory Direct 7-30 Days Lead Time MOQ: 100KG Global Export

Introduction

CAS Number: 96-43-5

Molecular Formula: C4H3ClS

Molecular Weight: 118.58 g/mol

Appearance: Colorless liquid

Melting Point: -71.9°C

Boiling Point: 127-129°C

Usage: Widely used as an intermediate in the synthesis of pharmaceuticals and agrochemicals.

 

Aspect Details
Name 2-Chlorothiophene
Common Synonyms 2-Chlorothiolen, Thienyl chloride (2-position)
CAS No. 5268-17-5
Molecular Formula C₄H₃ClS
Molecular Weight 118.59 g/mol
Physical Properties
  • Appearance: Colorless to pale yellow liquid
  • Boiling Point: 143-145 °C
  • Melting Point: -56 °C
  • Solubility: Slightly soluble in water; soluble in organic solvents (e.g., ethanol, ether)
  • Density: 1.28 g/cm³
Chemical Properties
  • Contains a chlorine atom and a thiophene ring (five-membered heterocycle with sulfur)
  • Exhibits electrophilic substitution reactivity due to the electron-rich thiophene ring
  • Undergoes nucleophilic substitution at the chlorine position under suitable conditions
  • Stable under normal conditions but may react with strong nucleophiles or bases
Applications
  • Used as an intermediate in pharmaceutical synthesis (e.g., antiviral and antifungal agents)
  • Employed in agrochemicals as a building block for herbicides and pesticides
  • Utilized in organic synthesis for the preparation of polymers and specialty chemicals
Safety Information
  • GHS Hazards: H302 (harmful if swallowed), H315 (causes skin irritation)
  • Precautionary Measures: Avoid inhalation and contact with eyes; use PPE
  • Storage: Keep in a tightly sealed container in a cool, well-ventilated area

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