2-Chlorothiophene-5-carboxylic acid Cas：24065-33-6
Pharmaceutical Materials 2025-03-02
2-Chlorothiophene-5-carboxylic acid, with the CAS number 24065-33-6, is a versatile organic compound that finds applications in both the pharmaceutical and chemical industries. This compound, also known as 5-chlorothiophene-2-carboxylic acid, possesses a chlorine atom substituted on the thiophene ring, imparting unique chemical properties.
It is primarily used as an intermediate in the synthesis of various pharmaceuticals, particularly in the development of anticoagulants such as rivaroxaban. Additionally, it serves as a valuable building block in organic synthesis due to its reactive carboxylic acid group. 2-Chlorothiophene-5-carboxylic acid is typically a white to off-white solid powder with a distinct melting point and boiling point, making it easy to identify and handle in laboratory settings.
| Product Information | Details |
|---|---|
| Compound Name | 2-Chlorothiophene-5-carboxylic acid |
| CAS Number | 24065-33-6 |
| Molecular Formula | C5H3ClO2S |
| Molecular Weight | 162.59 g/mol |
| Physical State | White to off-white solid powder |
| Melting Point | 146-158°C |
| Boiling Point | 287°C at 760 mmHg |
| Density | 1.572 g/cm³ |
| Flash Point | 127.4°C |
| Vapor Pressure | 0.00119 mmHg at 25°C |
| Solubility | Soluble in DMSO and methanol (sparingly) |
| Usage | Pharmaceutical intermediate, organic synthesis building block |
| Storage Conditions | Store in a cool, dry place, away from light and moisture. |
| Safety Information | May cause skin irritation and serious eye irritation. Handle with care. |
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